Grepafloxacin

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Grepafloxacin
Systematic (IUPAC) name
1-cyclopropyl-6-fluoro-5-methyl-7-(3-methylpiperazin-1-yl)- 4-oxo-quinoline- 3-carboxylic acid
Identifiers
CAS number	119914-60-2
ATC code	J01MA11
PubChem	72474
DrugBank	APRD01003
Chemical data
Formula	C19H22FN3O3
Mol. mass	359.395 g/mol
Pharmacokinetic data
Bioavailability	?
Protein binding	50%
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

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Definitions
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List of terms related to Grepafloxacin

Grepafloxacin hydrochloride (Raxar®, Glaxo Wellcome) is an oral broad-spectrum quinoline antibacterial agent used to treat bacterial infections. Grepafloxacin was withdrawn in the United States due to its side effect of lengthening the QT interval on the electrocardiogram, leading to cardiac events and sudden death.

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