Fungemia
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| Fungemia Classification and external resources | |
| ICD-9 | 117.9 |
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| MeSH | D016469 |
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Ongoing Trials on Fungemia at Clinical Trials.gov Clinical Trials on Fungemia at Google
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US National Guidelines Clearinghouse on Fungemia
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Directions to Hospitals Treating Fungemia Risk calculators and risk factors for Fungemia
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Fungemia (also known as Candidemia, Candedemia, and Invasive Candidiasis) is the presence of fungi or yeasts in the blood. It is most commonly seen in immunosuppressed or immunocompromised patients with severe neutropenia, oncology patients, or in patients with intravenous catheters. Recently, it has been suggested the otherwise immunocompetent patients taking infliximab may be at a higher risk for fungemia.
The diagnosis is complicated, as routine blood cultures have poor sensitivity. Treatment involves use of antifungals, e.g. fluconazole or amphotericin.
The two most important risk factors are:
- Use of broad-spectrum antibiotics
- Colonization by fungi (see e.g. candidiasis)
Other risk factors are:
- Dialysis
- Diabetes
- Lowered intestinal flora
- Suppressed Immune system
- Central venous catheter
- High severity of illness
- Multiple abdominal surgeries
- Use of steroids
- burns
The most commonly known pathogen is Candida albicans, causing roughly 70% of fungemias, followed by Torulopsis glabrata with 10%, and Aspergillus with 1%. However, the frequency of infection by T. glabrata, Candida tropicalis, C. krusei, and C. parapsilosis is increasing, especially when significant use of fluconazole is common.
Symptoms can range from mild to extreme, often described as extreme flu-like symptoms. Pain, mental disorders, chronic fatigue, infections, are a few of the long list of associated symptoms with Fungemia.
See also
External link
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
