Fungemia
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| Fungemia Classification and external resources | |
| ICD-9 | 117.9 |
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| MeSH | D016469 |
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WikiDoc Resources for Fungemia | |
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Most recent articles on Fungemia | |
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Evidence Based Medicine | |
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Clinical Trials | |
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Ongoing Trials on Fungemia at Clinical Trials.gov Clinical Trials on Fungemia at Google
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Guidelines / Policies / Govt | |
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US National Guidelines Clearinghouse on Fungemia
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Definitions | |
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Patient Resources / Community | |
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Directions to Hospitals Treating Fungemia Risk calculators and risk factors for Fungemia
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Healthcare Provider Resources | |
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Causes & Risk Factors for Fungemia | |
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Continuing Medical Education (CME) | |
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Experimental / Informatics | |
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Overview
Fungemia (also known as Candidemia, Candedemia, and Invasive Candidiasis) is the presence of fungi or yeasts in the blood. It is most commonly seen in immunosuppressed or immunocompromised patients with severe neutropenia, oncology patients, or in patients with intravenous catheters. Recently, it has been suggested the otherwise immunocompetent patients taking infliximab may be at a higher risk for fungemia.
Risk factors
The two most important risk factors are:
- Use of broad-spectrum antibiotics
- Colonization by fungi (see e.g. candidiasis)
Other risk factors include:
- Dialysis
- Diabetes
- Lowered intestinal flora
- Suppressed Immune system
- Central venous catheter
- High severity of illness
- Multiple abdominal surgeries
- Use of steroids
- burns
Differential diagnosis of most common pathogens
The most commonly known pathogen is Candida albicans, causing roughly 70% of fungemias, followed by Candida glabrata with 10%, and Aspergillus with 1%. However, the frequency of infection by T. glabrata, Candida tropicalis, C. krusei, and C. parapsilosis is increasing, especially when significant use of fluconazole is common.
Signs and symptoms
Symptoms can range from mild to extreme, often described as extreme flu-like symptoms. Pain, mental disorders, chronic fatigue, infections, are a few of the long list of associated symptoms with Fungemia.
Diagnosis
The diagnosis is complicated, as routine blood cultures have poor sensitivity.
Treatment
Treatment involves use of antifungals, e.g. fluconazole or amphotericin.
See also
External link
WikiDoc Research Resources for Fungemia | |
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| Articles on Fungemia | Most recent articles on Fungemia • Most cited articles on Fungemia • Review articles on Fungemia • Articles on Fungemia in N Eng J Med, Lancet, BMJ |
| Media (Slides, Video, Images, MP3) on Fungemia | Powerpoint slides on Fungemia • Images of Fungemia • Photos of Fungemia • Podcasts & MP3s on Fungemia • Videos on Fungemia |
| Evidence Based Medicine Regarding Fungemia | Cochrane Collaboration on Fungemia • Bandolier on Fungemia • TRIP on Fungemia |
| Cost Effectiveness of Fungemia | Cost Effectiveness of Fungemia |
| Clinical Trials Involving Fungemia | Ongoing Trials on Fungemia at Clinical Trials.gov • Trial results on Fungemia • Clinical Trials on Fungemia at Google |
| Guidelines / Policies / Government Resources (FDA/CDC) Regarding Fungemia | US National Guidelines Clearinghouse on Fungemia • NICE Guidance on Fungemia • NHS PRODIGY Guidance • FDA on Fungemia • CDC on Fungemia |
| Textbook Information on Fungemia | Books and Textbook Information on Fungemia |
| Pharmacology Resources on Fungemia | Dosing of Fungemia • Drug interactions with Fungemia • Side effects of Fungemia • Allergic reactions to Fungemia • Overdose information on Fungemia • Carcinogenicity information on Fungemia • Fungemia in pregnancy • Pharmacokinetics of Fungemia • |
| Genetics, Pharmacogenomics, and Proteinomics of Fungemia | Genetics of Fungemia • Pharmacogenomics of Fungemia • Proteomics of Fungemia |
| Newstories on Fungemia | Fungemia in the news • Be alerted to news on Fungemia • News trends on Fungemia |
| Commentary on Fungemia | Blogs on Fungemia |
| Patient Resources on Fungemia | Patient resources on Fungemia • Discussion groups on Fungemia • Patient Handouts on Fungemia • Directions to Hospitals Treating Fungemia • Risk calculators and risk factors for Fungemia |
| Healthcare Provider Resources on Fungemia | Symptoms of Fungemia • Causes & Risk Factors for Fungemia • Diagnostic studies for Fungemia • Treatment of Fungemia |
| Continuing Medical Education (CME) Programs on Fungemia | CME Programs on Fungemia |
| International Resources on Fungemia | Fungemia en Espanol • Fungemia en Francais |
| Business Resources on Fungemia | Fungemia in the Marketplace • Patents on Fungemia |
| Informatics Resources on Fungemia | List of terms related to Fungemia |
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Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
