Functional residual capacity

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Evidence Based Medicine
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Functional Residual Capacity (FRC) is the volume of air present in the lungs at the end of passive expiration. At FRC, the elastic recoil forces of the lungs and chest wall are equal but opposite and there is no exertion by the diaphragm or other respiratory muscles.

FRC is the sum of Expiratory Reserve Volume (ERV) and Residual Volume (RV) and measures approximately 2400 ml in a 70 kg, average-sized male. It can be estimated through spirometry, but in order to measure it more precisely, one would need to perform a test that directly measures RV such as nitrogen washout, helium dilution or body plethysmography.

A lowered or elevated FRC is often an indication of some form of respiratory disease. For instance, in emphysema, the lungs are more compliant and therefore are more susceptible to the outward recoil forces of the chest wall. Emphysema patients often have noticeably broader chests because they are breathing at larger volumes.

External links

• Functional+residual+capacity at eMedicine Dictionary

v • d • e Respiratory system, physiology: respiratory physiology
Volumes	lung volumes - vital capacity - functional residual capacity - respiratory minute volume - closing capacity - dead space - spirometry - body plethysmography - peak flow meter - thoracic independent volume - bronchial challenge test
Airways	ventilation (V) (positive pressure) - breath (inhalation, exhalation) -respiratory rate - respirometer - pulmonary surfactant - compliance - hysteresivity - airway resistance
Blood	pulmonary circulation - perfusion (Q) - hypoxic pulmonary vasoconstriction - pulmonary shunt
Interactions	ventilation/perfusion ratio (V/Q) and scan - zones of the lung - gas exchange - pulmonary gas pressures - alveolar gas equation - hemoglobin - oxygen-haemoglobin dissociation curve (2,3-DPG, Bohr effect, Haldane effect) - carbonic anhydrase (chloride shift) - oxyhemoglobin - respiratory quotient - arterial blood gas - diffusion capacity - Dlco
Control of respiration	pons (pneumotaxic center, apneustic center) - medulla (dorsal respiratory group, ventral respiratory group) - chemoreceptors (central, peripheral) - pulmonary stretch receptors (Hering-Breuer reflex)
Insufficiency	high altitude - oxygen toxicity - hypoxia

v • d • e WikiDoc Research Resources for Functional residual capacity (Click show to right to view)
Articles on Functional residual capacity	Most recent articles on Functional residual capacity • Most cited articles on Functional residual capacity • Review articles on Functional residual capacity • Articles on Functional residual capacity in N Eng J Med, Lancet, BMJ
Media (Slides, Video, Images, MP3) on Functional residual capacity	Powerpoint slides on Functional residual capacity • Images of Functional residual capacity • Photos of Functional residual capacity • Podcasts & MP3s on Functional residual capacity • Videos on Functional residual capacity
Evidence Based Medicine Regarding Functional residual capacity	Cochrane Collaboration on Functional residual capacity • Bandolier on Functional residual capacity • TRIP on Functional residual capacity
Cost Effectiveness of Functional residual capacity	Cost Effectiveness of Functional residual capacity
Clinical Trials Involving Functional residual capacity	Ongoing Trials on Functional residual capacity at Clinical Trials.gov • Trial results on Functional residual capacity • Clinical Trials on Functional residual capacity at Google
Guidelines / Policies / Government Resources (FDA/CDC) Regarding Functional residual capacity	US National Guidelines Clearinghouse on Functional residual capacity • NICE Guidance on Functional residual capacity • NHS PRODIGY Guidance • FDA on Functional residual capacity • CDC on Functional residual capacity
Textbook Information on Functional residual capacity	Books and Textbook Information on Functional residual capacity
Pharmacology Resources on Functional residual capacity	Dosing of Functional residual capacity • Drug interactions with Functional residual capacity • Side effects of Functional residual capacity • Allergic reactions to Functional residual capacity • Overdose information on Functional residual capacity • Carcinogenicity information on Functional residual capacity • Functional residual capacity in pregnancy • Pharmacokinetics of Functional residual capacity •
Genetics, Pharmacogenomics, and Proteinomics of Functional residual capacity	Genetics of Functional residual capacity • Pharmacogenomics of Functional residual capacity • Proteomics of Functional residual capacity
Newstories on Functional residual capacity	Functional residual capacity in the news • Be alerted to news on Functional residual capacity • News trends on Functional residual capacity
Commentary on Functional residual capacity	Blogs on Functional residual capacity
Patient Resources on Functional residual capacity	Patient resources on Functional residual capacity • Discussion groups on Functional residual capacity • Patient Handouts on Functional residual capacity • Directions to Hospitals Treating Functional residual capacity • Risk calculators and risk factors for Functional residual capacity
Healthcare Provider Resources on Functional residual capacity	Symptoms of Functional residual capacity • Causes & Risk Factors for Functional residual capacity • Diagnostic studies for Functional residual capacity • Treatment of Functional residual capacity
Continuing Medical Education (CME) Programs on Functional residual capacity	CME Programs on Functional residual capacity
International Resources on Functional residual capacity	Functional residual capacity en Espanol • Functional residual capacity en Francais
Business Resources on Functional residual capacity	Functional residual capacity in the Marketplace • Patents on Functional residual capacity
Informatics Resources on Functional residual capacity	List of terms related to Functional residual capacity

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Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .