Airway resistance

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Airway resistance is a concept used in respiratory physiology to describe mechanical factors which limit the access of inspired air to the pulmonary alveoli, and thus determine airflow.

Resistance is greatest at the bronchi of intermediate size, in between the fourth and eighth bifurcation.[1]

Because airway resistance is dictated by the diameter of the airways and by the density of the inspired gas, the low density of heliox reduces airway resistance, and makes it easier to ventilage the lungs.

Resistance can be calculated using Ohm's law[2] or Poiseuille's law.[3]

Ohm's law

R = \frac {\Delta P}{V^*} = \frac {P_{mouth} - P_{alveoli}}{V^*}
  • R = resistance
  • P = pressure
  • V* = airflow (the asterisk should be read as a dot over the letter, which is used to denote rate in respiratory physiology.)

Poiseuille's law

 R = \frac{8nl}{\pi r^{4}}

(rewrite)

  • R = resistance
  • n = viscosity
  • l = length
  • r = radius

Because of the fourth power in the denominator, resistance increases rapidly as diameter decreases.

See also

References

  1. Physiology at MCG 4/4ch2/s4ch2_51
  2. Physiology at MCG 4/4ch2/s4ch2_46
  3. Physiology at MCG 4/4ch2/s4ch2_47

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Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

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