Fastigial nucleus

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Brain: Fastigial nucleus
Sagittal section through right cerebellar hemisphere. The right olive has also been cut sagitally. (Fastigial nucleus visible but not labeled.)
Latin nucleus fastigii
Gray's subject #187 796
Part of cerebellum
NeuroNames hier-687
Dorlands/Elsevier n_11/12581208

The nucleus fastigius is located in the cerebellum. It is made up of the nucleus dentatus, nucleus emboliformis, nucleus globosus, and nucleus fastigii, and is grey matter embedded in the white matter of the cerebellum.[1]

The fastigial nucleus or nucleus fastigii refers specifically to the concentration of gray matter nearest to the middle line at the anterior end of the superior vermis, and immediately over the roof of the fourth ventricle, from which it is separated by a thin layer of white matter.[2] It is smaller than the nucleus dentatus, but somewhat larger than the nucleus emboliformis and nucleus globosus, the other two independent centers of gray matter in the cerebellum.

The fastigial nucleus receives its afferent input from the flocculonodular lobe and the vermis. Most of its efferent connections travel via the inferior cerebellar peduncle to the vestibular nuclei, which is located at the junction of the pons and medulla.

The fastigial nucleus deals with antigravity muscle groups and other synergies involved with standing and walking.[3]


  1. "Medical Dictionary Online". Retrieved 2007-06-28.
  2. John K. Harting, Ph.D. (1997). "The Global Cerebellum '97". University of Wisconsin Medical School. Retrieved 2007-06-28.
  3. James D. Geyer, Janice M. Keating, Daniel C. Potts (1998). Neurology for the Boards. Lippincott-Raven. p. 9. Unknown parameter |city= ignored (help)

External links

This article was originally based on an entry from a public domain edition of Gray's Anatomy. As such, some of the information contained herein may be outdated. Please edit the article if this is the case, and feel free to remove this notice when it is no longer relevant.

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