Extramammary Paget's disease overview

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Extramammary Paget’s disease (EMPD), also Extramammary Paget disease, is a usually non-invasive adenocarcinoma of the skin outside of the mammary gland and includes Paget's disease of the vulva and Paget's disease of the penis. The origin of the neoplastic cells could be apocrine glands or epithelial stem cells. Skin areas rich in apocrine glands such as the genital region are typical sites of EMPD.