Extramammary Paget's disease epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]

Overview

Extramammary Paget's disease is rare, and its exact incidence is unknown. Extramammary Paget's disease commonly affects individuals 50-60 years of age. Females are more commonly affected with the disease than males. The female to male ratio is approximately 3-4.5 to 1. It usually affects individuals of the Caucasian race, but it may occur in other races.

Epidemiology and Demographics

Incidence

  • Extramammary Paget's disease is rare, and the exact incidence is unknown.
  • The incidence of extramammary Paget's disease is estimated to be 0.10 per 100,000 individuals.
  • However, in older reports, it represented 6.5% of all cases of all Paget diseases.

Age

  • The peak age incidence of vulvar extramammary Paget's disease is approximately 50-65 years.[1][2]
  • The median age for a diagnosis of scrotal and penile disease is approximately 70-75 years.

Gender

Females are more commonly affected with extramammary Paget's disease than males. The female to male ratio is approximately 3-4.5 to 1.[3]

Race

Extramammary Paget's disease usually affects individuals of the Caucasian race, but it may occur in other races.[4]

References

  1. Curtin JP, Rubin SC, Jones WB, Hoskins WJ, Lewis JL (1990). "Paget's disease of the vulva". Gynecol Oncol. 39 (3): 374–7. PMID 2175288.
  2. Lloyd J, Flanagan AM (2000). "Mammary and extramammary Paget's disease". J Clin Pathol. 53 (10): 742–9. PMC 1731095. PMID 11064666.
  3. Chanda JJ (1985). "Extramammary Paget's disease: prognosis and relationship to internal malignancy". J Am Acad Dermatol. 13 (6): 1009–14. PMID 3001158.
  4. Zollo, J.D.; Zeitouni, N.C. (2000). "The Roswell Park Cancer Institute experience with extramammary Paget's disease". British Journal of Dermatology. 142 (1): 59–65. doi:10.1046/j.1365-2133.2000.03242.x. ISSN 0007-0963.


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