Dyslipidemia
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| Dyslipidemia Classification and external resources | ||
| ICD-10 | E78. | |
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| ICD-9 | 272 | |
| MeSH | C18.452.339 | |
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Overview
Dyslipidemia is a disruption in the amount of lipids in the blood.
In western societies, most dyslipidemias are hyperlipidemias; that is, an elevation of lipids in the blood, often due to diet and lifestyle. The prolonged elevation of insulin levels can lead to dyslipidemia.
Classification
There are two major ways in which dyslipidemias are classified:
- Phenotype, or the presentation in the body (including the specific type of lipid that is increased)
- Etiology, or the reason for the condition (genetic, or secondary to another condition.) This classification can be problematic, because most conditions involve the intersection of genetics and lifestyle issues. However, there are a few well defined genetic conditions that are usually easy to identify.
Types
Increases
- These conditions are discussed in greater detail at hyperlipidemia.
- Hyperlipidemia: lipids
- Hypercholesterolemia: cholesterol
- Hypertriglyceridemia: triglycerides
- Hyperlipoproteinemia: lipoproteins (usually LDL unless otherwise specified)
- Hyperchylomicronemia: chylomicrons
- Combined hyperlipidemia: both LDL and triglycerides
Familial hypercholesterolemia is a specific form of hypercholesterolemia due to a defect on chromosome 19 (19p13.1-13.3).
Decreases
- Hypolipoproteinemia: lipoproteins
- Hypocholesterolemia: cholesterol
- Abetalipoproteinemia: beta lipoproteins
- Tangier disease: high density lipoprotein
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
