Duodenal atresia natural history, complications and prognosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Hamid Qazi, MD, BSc [2]
Overview
The symptoms of duodenal atresia usually develop in the first 48 hours of life, and start with symptoms such as bilious vomiting in 80% of the cases. Prognosis is generally very good, and the survival rate of patients with duodenal atresia is approximately 90%.
Natural History, Complications, and Prognosis
Natural History
- The symptoms of duodenal atresia usually develop in the first 48 hours of life, and start with symptoms such as vomiting.[1]
- Bilious vomiting in 80% of the cases.
- Non-bilious vomiting in 20% of the cases.
- Dehydration
- If duodenal atresia is left untreated it will result in death.
Complications
The complications of duodenal atresia are as follows:[2][3]
- There are no complications associated with duodenal atresia, however post surgical complications may occur.
- Post surgical complications include:
- Adhesions
- Duodenal dysmotility
- Megaduodenum with blind loop syndrome
- Duodenogastric reflux and gastritis
- Peptic ulcer disease
- Gastroesophageal reflux
- Cholelithiasis
- Cholecystitis
Prognosis
- Prognosis is generally good, and the survival rate of patients with duodenal atresia is approximately 90% after surgery.[4]
References
- ↑ Adams, Stephen D.; Stanton, Michael P. (2014). "Malrotation and intestinal atresias". Early Human Development. 90 (12): 921–925. doi:10.1016/j.earlhumdev.2014.09.017. ISSN 0378-3782.
- ↑ Spigland N, Yazbeck S (1990). "Complications associated with surgical treatment of congenital intrinsic duodenal obstruction". J Pediatr Surg. 25 (11): 1127–30. PMID 2273425.
- ↑ Kokkonen ML, Kalima T, Jääskeläinen J, Louhimo I (1988). "Duodenal atresia: late follow-up". J Pediatr Surg. 23 (3): 216–20. PMID 3357136.
- ↑ Escobar MA, Ladd AP, Grosfeld JL, West KW, Rescorla FJ, Scherer LR; et al. (2004). "Duodenal atresia and stenosis: long-term follow-up over 30 years". J Pediatr Surg. 39 (6): 867–71, discussion 867-71. PMID 15185215.