D-amino acid oxidase
|Locus||Chr. 12 q24|
D-amino acid oxidase (DAAO) is a peroxisomal enzyme containing FAD as cofactor spread from yeasts to human. It is not present in bacteria nor in plants. Its function is to oxidize D-amino acids to the corresponding imino acids producing ammonia and oxygen peroxide. Recently mammalian D-amino acid has been connected to the brain D-serine metabolism and to the regulation of the glutamatergic neurotransmission.
- Pollegioni L. et al (2007). "Physiological functions of D-amino acid oxidases: from yeast to humans.". Cell Mol Life Sci 64 (11): 1373-94. PMID 17396222.
CH-NH2 oxidoreductases (EC 1.4) - primarily amino acid oxidoreductases
|1.4.1 - NAD/NADP acceptor||Glutamate dehydrogenase (GLUD1)|
|1.4.3 - oxygen acceptor||D-amino acid oxidase - Amine oxidase - Lysyl oxidase - Monoamine oxidase|
|1.4.4 - disulfide acceptor||Glycine decarboxylase complex|
|1.4.99 - other acceptors||D-amino acid dehydrogenase - Amine dehydrogenase|
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