Central pontine myelinolysis risk factors

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]

Overview

The most potent risk factor in the development of central pontine myelinolysis is hyponatremia. Other risk factors include: Liver dysfunction and liver diseases, hypocholesterolemia, alcoholism, malnutrition, systemic medical disease and hemodialysis.

Risk Factors

Common Risk Factors

References

  1. Lee EM, Kang JK, Yun SC, Kim KH, Kim SJ, Hwang KS; et al. (2009). "Risk factors for central pontine and extrapontine myelinolysis following orthotopic liver transplantation". Eur Neurol. 62 (6): 362–8. doi:10.1159/000242426. PMID 19797900.
  2. Jacob S, Gupta H, Nikolic D, Gundogdu B, Ong S (2014). "Central pontine and extrapontine myelinolysis: the great masquerader-an autopsy case report". Case Rep Neurol Med. 2014: 745347. doi:10.1155/2014/745347. PMC 3970353. PMID 24716023.
  3. Martin RJ (2004). "Central pontine and extrapontine myelinolysis: the osmotic demyelination syndromes". J Neurol Neurosurg Psychiatry. 75 Suppl 3: iii22–8. doi:10.1136/jnnp.2004.045906. PMC 1765665. PMID 15316041.
  4. Oo TN, Smith CL, Swan SK (2003). "Does uremia protect against the demyelination associated with correction of hyponatremia during hemodialysis? A case report and literature review". Semin Dial. 16 (1): 68–71. PMID 12535304.

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