CAD (gene)
| carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
| |
| Identifiers | |
| Symbol | CAD |
| Entrez | 790 |
| HUGO | 1424 |
| OMIM | 114010 |
| RefSeq | NM_004341 |
| UniProt | P27708 |
| Other data | |
| EC number | 2.1.3.2 |
| Locus | Chr. 2 p21 |
CAD is a gene which encodes several enzymes involved in pyrimidine biosynthesis. De-novo synthesis starts with cytosolic carbamoylphosphate synthetase II which uses glutamine, carbon dioxide and 2 ATP. This enzyme is inhibited by UTP.
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