|carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase|
|Locus||Chr. 2 p21|
CAD is a gene which encodes several enzymes involved in pyrimidine biosynthesis. De-novo synthesis starts with cytosolic carbamoylphosphate synthetase II which uses glutamine, carbon dioxide and 2 ATP. This enzyme is inhibited by UTP.
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