Botryomycosis

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Botryomycosis

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Botryomycosis; also known as bacterial pseudomycosis is a rare chronic granulomatous bacterial infection that affects the skin, and sometimes the viscera. The disease was originally discovered by Otto Bollinger (1843-1909) in 1870, and its name was coined by Sebastiano Rivolta (1832-1893) in 1884. The name refers to its grape-like granules (Gr. botryo = grapes) and the mistakenly believed fungal etiology (Gr. mykes = fungus). In 1919 the bacterial origin of the infection was discovered. Botryomycosis has been known to affect humans, horses, cattle and swine.

Staphylococcus aureus is usually the organism that causes the infection, however it can also be caused by Pseudomonas aeruginosa or several other species of bacteria. The anatomic structure of its lesion is similar to that of actinomycosis and mycetoma, and its granules resemble the sulfur granules of actinomycosis.

There are only a handful of documented cases of botryomycosis in humans, and its pathogenesis is not completely understood. However, it is usually described in individuals with impaired immunity, or with an underlying disease such as diabetes mellitus, cystic fibrosis or HIV infection.

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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

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