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==Historical Perspective==
==Historical Perspective==
*In 1955, Zollinger and Ellison published their seminal paper on [[gastrinoma]] wherein the Zollinger-Ellison syndrome was first discussed. <ref name="pmid19653250">{{cite journal| author=Yeung MJ, Pasieka JL| title=Gastrinomas: a historical perspective. | journal=J Surg Oncol | year= 2009 | volume= 100 | issue= 5 | pages= 425-33 | pmid=19653250 | doi=10.1002/jso.21359 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19653250 }} </ref><ref name="pmid19836486">{{cite journal| author=Morrow EH, Norton JA| title=Surgical management of Zollinger-Ellison syndrome; state of the art. | journal=Surg Clin North Am | year= 2009 | volume= 89 | issue= 5 | pages= 1091-103 | pmid=19836486 | doi=10.1016/j.suc.2009.06.018 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19836486 }} </ref>
* In 1955, Zollinger and Ellison announced their concept about ulcerogenic islet cell tumor which caused marked ulcer diathesis due to gastric hyperacidity.<ref name="pmid1746876">{{cite journal| author=Zollinger RM| title=[The history of the Zollinger-Ellison syndrome]. | journal=Ann Gastroenterol Hepatol (Paris) | year= 1991 | volume= 27 | issue= 5 | pages= 223-6 | pmid=1746876 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1746876  }} </ref>
* Dr. Robert M. Zollinger and Dr. Edwin H. Ellison announced their theory at annual meeting of the American Surgical Association in Philadelphia in April 1956.<ref name="pmid13259432">{{cite journal| author=ZOLLINGER RM, ELLISON EH| title=Primary peptic ulcerations of the jejunum associated with islet cell tumors of the pancreas. | journal=Ann Surg | year= 1955 | volume= 142 | issue= 4 | pages= 709-23; discussion, 724-8 | pmid=13259432 | doi= | pmc=1465210 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=13259432 }} </ref>
* This concept raised from clinical case of two women who presented with perforated jejunal ulcers accompanied with severe ulcer diathesis.
* In 1960s, gastrin was described as a main pathogenesis of gastric hyperacidity.<ref name="pmid17053435">{{cite journal| author=Hou W, Schubert ML| title=Gastric secretion. | journal=Curr Opin Gastroenterol | year= 2006 | volume= 22 | issue= 6 | pages= 593-8 | pmid=17053435 | doi=10.1097/01.mog.0000245538.43142.87 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17053435 }} </ref>
*


==References==
==References==

Revision as of 15:04, 15 March 2019

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Aravind Reddy Kothagadi M.B.B.S[2]

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Overview

In 1955, Zollinger and Ellison published their seminal paper on gastrinomas wherein the Zollinger-Ellison syndrome was first discussed.

Historical Perspective

  • In 1955, Zollinger and Ellison announced their concept about ulcerogenic islet cell tumor which caused marked ulcer diathesis due to gastric hyperacidity.[1]
  • Dr. Robert M. Zollinger and Dr. Edwin H. Ellison announced their theory at annual meeting of the American Surgical Association in Philadelphia in April 1956.[2]
  • This concept raised from clinical case of two women who presented with perforated jejunal ulcers accompanied with severe ulcer diathesis.
  • In 1960s, gastrin was described as a main pathogenesis of gastric hyperacidity.[3]

References

  1. Zollinger RM (1991). "[The history of the Zollinger-Ellison syndrome]". Ann Gastroenterol Hepatol (Paris). 27 (5): 223–6. PMID 1746876.
  2. ZOLLINGER RM, ELLISON EH (1955). "Primary peptic ulcerations of the jejunum associated with islet cell tumors of the pancreas". Ann Surg. 142 (4): 709–23, discussion, 724–8. PMC 1465210. PMID 13259432.
  3. Hou W, Schubert ML (2006). "Gastric secretion". Curr Opin Gastroenterol. 22 (6): 593–8. doi:10.1097/01.mog.0000245538.43142.87. PMID 17053435.

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