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{{Yersinia pestis infection}}
{{Yersinia pestis infection}}
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==Overview==
Apart from the presence of [[bubo]]es, which are tender [[lymph node]]s in patients infected with bubonic plague, the physical examination findings are not specific to plague. Nonetheless, physical examination is crucial to evaluate for the presence of target organ damage or the progression and worsening of infection burden in these patients.<ref name=CDC>{{cite web |url=http://www.cdc.gov/plague/symptoms/index.html |title= Plague |date= Jun 13 2012 |website= Centers for Disease Control and Prevention|publisher=CDC|accessdate=Jul 25 2014}}</ref>
 
==Physical Examination==
[[Bubo]]es, which are fixed tender [[lymphadenopathy]] in patients with bubonic plague, are characteristic findings on physical examination.<ref name=CDC>{{cite web |url=http://www.cdc.gov/plague/symptoms/index.html |title= Plague |date= Jun 13 2012 |website= Centers for Disease Control and Prevention|publisher=CDC|accessdate=Jul 25 2014}}</ref> Otherwise, patients with plague infection generally have non-specific physical examination findings. Nonetheless, physical examination is key in all cases of plague for the evaluation of the patient's clinical picture and monitoring for clinical response.<ref name=CDC>{{cite web |url=http://www.cdc.gov/plague/symptoms/index.html |title= Plague |date= Jun 13 2012 |website= Centers for Disease Control and Prevention|publisher=CDC|accessdate=Jul 25 2014}}</ref>
 
===General Appearance===
Patients infected with plague are generally toxic-looking.
 
===Vital Signs===
*[[Fever]] is invariably present in all patients
*[[Tachycardia]]
*[[Tachypnea]]
*[[Hypotension]] in septicemic plague
 
===HEENT===
*Pharyngeal [[erythema]]
*[[Tonsils|Tonsilar]] enlargement
*[[Meningismus]] in plague complicated by meningitis
 
===Skin===
*[[Papule]]s, [[pustule]]s, [[ulcer]]s, or [[vesicle]]s surrounded by local [[erythema]] at site of infection
*Fixed tender [[lymphadenopathy]] of 1-10 cm in diameter in bubonic plague that may be present anywhere: axillary, cervical, postauricular, inguinal, epitrochlear, or popliteal. [[Lymph node]]s may demonstrate fluctuance, suppuration, and may eventually drain.
 
<gallery>
Image:Plague inguinal buboes.jpg| Inguinal lymphadenoapthy
 
Image:Axillary bubo.JPG| Axillary lymphadenopathy
</gallery>
 
===Chest===
*Auscultation may be minimal despite worsening infectious burden
*Dullness to percussion due to segmental pulmonary consolidation
*Decreased [[breath sound]]s over affected area
 
===Abdomen===
*Intra-abdominal [[bubo]]es may present with [[abdominal tenderness]], [[guarding]], or signs of peritoneal irritation, such as [[rebound tenderness]] and abdominal rigidity.
*[[Hepatomegaly]]
 
===Extremities===
*Black [[gangrene|gangrenous]] distal upper and lower extremities (shown below)
 
<gallery>
Image:Acral gangrene of digits -bubonic plague.jpg| Acral ganagre of the digits in bubonic plague
 
Image:Plague1.jpg| Dorsal view of a 59 year-old man’s right hand who had been infected by the plague bacterium, Yersinia pestis, after having come into contact with both an infected cat, and a dead mouse in his neighborhood.  <SMALL><SMALL>''[http://phil.cdc.gov/phil/ Adapted from Public Health Image Library (PHIL), Centers for Disease Control and Prevention.]''<ref name="PHIL">{{Cite web | title = Public Health Image Library (PHIL), Centers for Disease Control and Prevention | url = http://phil.cdc.gov/phil/}}</ref></SMALL></SMALL>
 
Image:Plague2.jpg| Dorsal view of a 59 year-old man’s hands who had been infected by the plague bacterium, Yersinia pestis, after having come into contact with both an infected cat, and a dead mouse in his neighborhood. <SMALL><SMALL>''[http://phil.cdc.gov/phil/ Adapted from Public Health Image Library (PHIL), Centers for Disease Control and Prevention.]''<ref name="PHIL">{{Cite web | title = Public Health Image Library (PHIL), Centers for Disease Control and Prevention | url = http://phil.cdc.gov/phil/}}</ref></SMALL></SMALL>
 
Image:Plague3.jpg| Palmar view of a 59 year-old man’s right hand who had been infected by the plague bacterium, Yersinia pestis, after having come into contact with both an infected cat, and a dead mouse in his neighborhood. <SMALL><SMALL>''[http://phil.cdc.gov/phil/  Adapted from Public Health Image Library (PHIL), Centers for Disease Control and Prevention.]''<ref name="PHIL">{{Cite web | title = Public Health Image Library (PHIL), Centers for Disease Control and Prevention | url = http://phil.cdc.gov/phil/}}</ref></SMALL></SMALL>
 
Image:Plague4.jpg| Dorsal view of a 59 year-old man’s feet who had been infected by the plague bacterium, Yersinia pestis, after having come into contact with both an infected cat, and a dead mouse in his neighborhood. <SMALL><SMALL>''[http://phil.cdc.gov/phil/  Adapted from Public Health Image Library (PHIL), Centers for Disease Control and Prevention.]''<ref name="PHIL">{{Cite web | title = Public Health Image Library (PHIL), Centers for Disease Control and Prevention | url = http://phil.cdc.gov/phil/}}</ref></SMALL></SMALL>
 
 
</gallery>
 
*Warm skin in septic patients
*[[Petechiae]] in patients with [[disseminated intravascular coagulopathy]] ([[DIC]])


==References==
==References==
 
{{reflist|2}}
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Latest revision as of 00:46, 30 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-In-Chief: Yazan Daaboul; Serge Korjian

Overview

Apart from the presence of buboes, which are tender lymph nodes in patients infected with bubonic plague, the physical examination findings are not specific to plague. Nonetheless, physical examination is crucial to evaluate for the presence of target organ damage or the progression and worsening of infection burden in these patients.[1]

Physical Examination

Buboes, which are fixed tender lymphadenopathy in patients with bubonic plague, are characteristic findings on physical examination.[1] Otherwise, patients with plague infection generally have non-specific physical examination findings. Nonetheless, physical examination is key in all cases of plague for the evaluation of the patient's clinical picture and monitoring for clinical response.[1]

General Appearance

Patients infected with plague are generally toxic-looking.

Vital Signs

HEENT

Skin

  • Papules, pustules, ulcers, or vesicles surrounded by local erythema at site of infection
  • Fixed tender lymphadenopathy of 1-10 cm in diameter in bubonic plague that may be present anywhere: axillary, cervical, postauricular, inguinal, epitrochlear, or popliteal. Lymph nodes may demonstrate fluctuance, suppuration, and may eventually drain.

Chest

  • Auscultation may be minimal despite worsening infectious burden
  • Dullness to percussion due to segmental pulmonary consolidation
  • Decreased breath sounds over affected area

Abdomen

Extremities

  • Black gangrenous distal upper and lower extremities (shown below)

References

  1. 1.0 1.1 1.2 "Plague". Centers for Disease Control and Prevention. CDC. Jun 13 2012. Retrieved Jul 25 2014. Check date values in: |accessdate=, |date= (help)
  2. 2.0 2.1 2.2 2.3 "Public Health Image Library (PHIL), Centers for Disease Control and Prevention".

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