Wild-type (senile) amyloidosis physical examination: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Wild-type (senile) amyloidosis}} | {{Wild-type (senile) amyloidosis}} | ||
{{CMG}} | {{CMG}}{{AE}}{{Sab}}{{JH}}{{RT}}; {{AN}}; {{CZ}}; {{LG}} | ||
==Overview== | ==Overview== | ||
[[Physical examination]] of [[Patient|patients]] with wild-type (senile) amyloidosis can be significant for the condition in question and can also translate the variety of [[Pathology|pathologies]] as a part of [[Ageing|aging]] and age-related [[Comorbidity|comorbidities]]. | |||
==Physical Examination== | ==Physical Examination== | ||
[[Physical examination]] of [[Patient|patients]] with wild-type (senile) amyloidosis can be significant for the condition in question and can also translate the variety of [[Pathology|pathologies]] as a part of [[Ageing|aging]] and age-related [[Comorbidity|comorbidities]]. | |||
===Appearance of the Patient=== | ===Appearance of the Patient=== | ||
*[[Patient|Patients]] with wild-type (senile) amyloidosis appear senile. | |||
*Exact appearance of the [[Patient|patients]] depend upon the severity of the condition. | |||
===Vital Signs=== | |||
* [[Hypertension]] | |||
* [[Tachycardia]] | |||
===Skin=== | ===Skin=== | ||
* [[Edema]] | |||
===HEENT=== | ===HEENT=== | ||
* HEENT [[Physical examination|examination]] of [[Patient|patients]] with wild-type (senile) amyloidosis is usually normal. | |||
===Neck=== | ===Neck=== | ||
* [[Jugular venous pressure|Elevated jugular pressure]]<ref name=":0">{{Cite journal | |||
| author = [[Belinda Ng]], [[Lawreen H. Connors]], [[Ravin Davidoff]], [[Martha Skinner]] & [[Rodney H. Falk]] | |||
| title = Senile systemic amyloidosis presenting with heart failure: a comparison with light chain-associated amyloidosis | |||
| journal = [[Archives of internal medicine]] | |||
| volume = 165 | |||
| issue = 12 | |||
| pages = 1425–1429 | |||
| year = 2005 | |||
| month = June | |||
| doi = 10.1001/archinte.165.12.1425 | |||
| pmid = 15983293 | |||
}}</ref> | |||
===Lungs=== | ===Lungs=== | ||
* [[Pulmonary examination]] of [[Patient|patients]] with wild-type (senile) amyloidosis is usually normal. | |||
===Heart=== | ===Heart=== | ||
*[[Third heart sound]] | |||
*[[Fourth heart sound]] | |||
*[[Arrhythmias]] <ref name="pmid17062380">{{cite journal |author=Rapezzi C, Perugini E, Salvi F, Grigioni F, Riva L, Cooke RM, Ferlini A, Rimessi P, Bacchi-Reggiani L, Ciliberti P, Pastorelli F, Leone O, Bartolomei I, Pinna AD, Arpesella G, Branzi A |title=Phenotypic and genotypic heterogeneity in transthyretin-related cardiac amyloidosis: towards tailoring of therapeutic strategies? |journal=[[Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis]] |volume=13 |issue=3 |pages=143–53 |year=2006 |month=September |pmid=17062380 |doi=10.1080/13506120600877136 |url=http://informahealthcare.com/doi/abs/10.1080/13506120600877136 |accessdate=2012-02-13}}</ref> | |||
*Auscultation may also reveal [[rales]], [[heart murmur]]s, and/or other pathologic heart sounds. | |||
*In patients with [[valvular heart disease]] involvement, murmurs of [[Mitral regurgitation|mitral]] and [[tricuspid regurgitation]] may be heard. | |||
===Abdomen=== | ===Abdomen=== | ||
*[[Hepatomegaly]] may be present in the setting of [[right heart failure]] | |||
*[[Ascites]] may be present in the setting of [[right heart failure]] | |||
*[[Splenomegaly]] is rare | |||
===Back=== | ===Back=== | ||
* [[Human back|Back]] [[Physical examination|examination]] of [[Patient|patients]] with wild-type (senile) amyloidosis is usually normal. | |||
===Genitourinary=== | ===Genitourinary=== | ||
* [[Genitourinary system|Genitourinary]] [[Physical examination|examination]] of [[Patient|patients]] with wild-type (senile) amyloidosis is usually normal. | |||
===Neuromuscular=== | ===Neuromuscular=== | ||
* [[Peripheral neuropathy]] | |||
===Extremities=== | ===Extremities=== | ||
* [[Peripheral edema]]<ref name=":02">{{Cite journal | |||
| author = [[Belinda Ng]], [[Lawreen H. Connors]], [[Ravin Davidoff]], [[Martha Skinner]] & [[Rodney H. Falk]] | |||
| title = Senile systemic amyloidosis presenting with heart failure: a comparison with light chain-associated amyloidosis | |||
| journal = [[Archives of internal medicine]] | |||
| volume = 165 | |||
| issue = 12 | |||
| pages = 1425–1429 | |||
| year = 2005 | |||
| month = June | |||
| doi = 10.1001/archinte.165.12.1425 | |||
| pmid = 15983293 | |||
}}</ref> | |||
==References== | ==References== |
Latest revision as of 21:20, 17 December 2019
Wild-type (senile) amyloidosis Microchapters |
Differentiating Wild-type (senile) amyloidosis from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sabawoon Mirwais, M.B.B.S, M.D.[2]Jesus Rosario Hernandez, M.D. [3]Raviteja Guddeti, M.B.B.S. [4]; Aarti Narayan, M.B.B.S [5]; Cafer Zorkun, M.D., Ph.D. [6]; Lakshmi Gopalakrishnan, M.B.B.S. [7]
Overview
Physical examination of patients with wild-type (senile) amyloidosis can be significant for the condition in question and can also translate the variety of pathologies as a part of aging and age-related comorbidities.
Physical Examination
Physical examination of patients with wild-type (senile) amyloidosis can be significant for the condition in question and can also translate the variety of pathologies as a part of aging and age-related comorbidities.
Appearance of the Patient
- Patients with wild-type (senile) amyloidosis appear senile.
- Exact appearance of the patients depend upon the severity of the condition.
Vital Signs
Skin
HEENT
- HEENT examination of patients with wild-type (senile) amyloidosis is usually normal.
Neck
Lungs
- Pulmonary examination of patients with wild-type (senile) amyloidosis is usually normal.
Heart
- Third heart sound
- Fourth heart sound
- Arrhythmias [2]
- Auscultation may also reveal rales, heart murmurs, and/or other pathologic heart sounds.
- In patients with valvular heart disease involvement, murmurs of mitral and tricuspid regurgitation may be heard.
Abdomen
- Hepatomegaly may be present in the setting of right heart failure
- Ascites may be present in the setting of right heart failure
- Splenomegaly is rare
Back
- Back examination of patients with wild-type (senile) amyloidosis is usually normal.
Genitourinary
- Genitourinary examination of patients with wild-type (senile) amyloidosis is usually normal.
Neuromuscular
Extremities
References
- ↑ Belinda Ng, Lawreen H. Connors, Ravin Davidoff, Martha Skinner & Rodney H. Falk (2005). "Senile systemic amyloidosis presenting with heart failure: a comparison with light chain-associated amyloidosis". Archives of internal medicine. 165 (12): 1425–1429. doi:10.1001/archinte.165.12.1425. PMID 15983293. Unknown parameter
|month=
ignored (help) - ↑ Rapezzi C, Perugini E, Salvi F, Grigioni F, Riva L, Cooke RM, Ferlini A, Rimessi P, Bacchi-Reggiani L, Ciliberti P, Pastorelli F, Leone O, Bartolomei I, Pinna AD, Arpesella G, Branzi A (2006). "Phenotypic and genotypic heterogeneity in transthyretin-related cardiac amyloidosis: towards tailoring of therapeutic strategies?". Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 13 (3): 143–53. doi:10.1080/13506120600877136. PMID 17062380. Retrieved 2012-02-13. Unknown parameter
|month=
ignored (help) - ↑ Belinda Ng, Lawreen H. Connors, Ravin Davidoff, Martha Skinner & Rodney H. Falk (2005). "Senile systemic amyloidosis presenting with heart failure: a comparison with light chain-associated amyloidosis". Archives of internal medicine. 165 (12): 1425–1429. doi:10.1001/archinte.165.12.1425. PMID 15983293. Unknown parameter
|month=
ignored (help)