VIPoma medical therapy: Difference between revisions

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{{CMG}}{{AE}}{{PSD}}
{{CMG}}{{AE}}{{PSD}}
==Overview==
==Overview==
Initial treatment in patient with VIPoma is prompt replacement of fluid and electrolyte losses. Steroids may be used to provide symptomatic relief.<ref name=sp>Vinik A. Vasoactive Intestinal Peptide Tumor (VIPoma) [Updated 2013 Nov 28]. In: De Groot LJ, Beck-Peccoz P, Chrousos G, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-. Available from: http://www.ncbi.nlm.nih.gov/books/NBK278960/</ref>
Initial treatment in patient with VIPoma is prompt replacement of fluid and electrolyte losses. [[Steroids]] may be used to provide symptomatic relief.<ref name=sp>Vinik A. Vasoactive Intestinal Peptide Tumor (VIPoma) [Updated 2013 Nov 28]. In: De Groot LJ, Beck-Peccoz P, Chrousos G, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-. Available from: http://www.ncbi.nlm.nih.gov/books/NBK278960/</ref>


==Medical Therapy==
==Medical Therapy==
*Initial treatment in patient with VIPoma is prompt replacement of fluid and electrolyte losses.  
*Initial treatment in patient with VIPoma is prompt replacement of fluid and electrolyte losses.  
 
*[[Sandostatin]] or [[chemotherapy]] must be considered for malignant tumors.
*Sandostatin or chemotherapy must be considered for malignant tumors.
*[[Steroids]] may be used to provide symptomatic relief.
 
*Prostaglandin synthesis inhibitors (e.g., [[indomethacin]]), [[phenothiazines]], and [[lithium]] combination may be used.
*Steroids may be used to provide symptomatic relief.
*Long-term [[octreotide]] treatment not only controls the [[diarrhea]] in the patients with VIPoma but also may cause arrest or regression of the tumor.
 
*Prostaglandin synthesis inhibitors (e.g., indomethacin), phenothiazines, and lithium combination may be used.
 
*Long-term octreotide treatment not only controls the diarrhea in the patients with VIPoma but also may cause arrest or regression of the tumor.


==References==
==References==

Revision as of 20:31, 27 October 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]

Overview

Initial treatment in patient with VIPoma is prompt replacement of fluid and electrolyte losses. Steroids may be used to provide symptomatic relief.[1]

Medical Therapy

  • Initial treatment in patient with VIPoma is prompt replacement of fluid and electrolyte losses.
  • Sandostatin or chemotherapy must be considered for malignant tumors.
  • Steroids may be used to provide symptomatic relief.
  • Prostaglandin synthesis inhibitors (e.g., indomethacin), phenothiazines, and lithium combination may be used.
  • Long-term octreotide treatment not only controls the diarrhea in the patients with VIPoma but also may cause arrest or regression of the tumor.

References

  1. Vinik A. Vasoactive Intestinal Peptide Tumor (VIPoma) [Updated 2013 Nov 28]. In: De Groot LJ, Beck-Peccoz P, Chrousos G, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-. Available from: http://www.ncbi.nlm.nih.gov/books/NBK278960/


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