Urinary incontinence pathophysiology: Difference between revisions

Jump to navigation Jump to search
Line 12: Line 12:


===Urinary incontinence in adults===
===Urinary incontinence in adults===
Continence and [[micturition]] involve a balance between outlet (urethra) and bladder [[detrusor]] muscle activity. Lower urinary tract function is often divided into filling and voiding phases.  Normally as the bladder fills the detrusor is compliant - stretching and increasing the volume it holds - without any unpleasant sensation and the outlet is closed.  At a socially acceptable time and place to void the bladder (detrusor) contracts and the outlet relaxes and flow ensues.  Any perturbation in that balance can lead to voiding dysfunction or incontinence.  Abnormal detrusor muscle activity or hypersensitivity of the bladder can lead to urge incontinence.  An incompetent outlet can lead to stress incontinence.  A bladder that cannot contract may lead to overflow incontinence.<ref name="urlpdfs.semanticscholar.org">{{cite web |url=https://pdfs.semanticscholar.org/0a01/f4ccaf0d943bd1d8d009b9d9ae6de1260511.pdf |title=pdfs.semanticscholar.org |format= |work= |accessdate=}}</ref>
Continence and [[micturition]] involve a balance between outlet (urethra) and bladder [[detrusor]] muscle activity. Lower urinary tract function is often divided into filling and voiding phases.  Normally as the bladder fills the detrusor is compliant - stretching and increasing the volume it holds - without any unpleasant sensation and the outlet is closed.  At a socially acceptable time and place to void the bladder (detrusor) contracts and the outlet relaxes and flow ensues.  Any perturbation in that balance can lead to voiding dysfunction or incontinence.  Abnormal detrusor muscle activity or hypersensitivity of the bladder can lead to urge incontinence.  An incompetent outlet can lead to stress incontinence.  A bladder that cannot contract may lead to overflow incontinence.<ref name="urlpdfs.semanticscholar.org">{{cite web |url=https://pdfs.semanticscholar.org/0a01/f4ccaf0d943bd1d8d009b9d9ae6de1260511.pdf |title=pdfs.semanticscholar.org |format= |work= |accessdate=}}</ref><ref name="pmid16702587">{{cite journal |vauthors=Brown JS, Bradley CS, Subak LL, Richter HE, Kraus SR, Brubaker L, Lin F, Vittinghoff E, Grady D |title=The sensitivity and specificity of a simple test to distinguish between urge and stress urinary incontinence |journal=Ann. Intern. Med. |volume=144 |issue=10 |pages=715–23 |date=May 2006 |pmid=16702587 |pmc=1557357 |doi= |url=}}</ref>


===Urinary incontinence in children===
===Urinary incontinence in children===

Revision as of 00:25, 14 September 2020

https://https://www.youtube.com/watch?v=vsLBApSlPMo&t=11s |350}}

Urinary incontinence Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Urinary incontinence from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic study of choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X-Ray Findings

Echocardiography and Ultrasound

CT scan

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Interventions

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Urinary incontinence pathophysiology On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Urinary incontinence pathophysiology

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Urinary incontinence pathophysiology

CDC on Urinary incontinence pathophysiology

Urinary incontinence pathophysiology in the news

Blogs on Urinary incontinence pathophysiology

Directions to Hospitals Treating Urinary incontinence

Risk calculators and risk factors for Urinary incontinence pathophysiology

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Pathophysiology

Urinary incontinence in adults

Continence and micturition involve a balance between outlet (urethra) and bladder detrusor muscle activity. Lower urinary tract function is often divided into filling and voiding phases. Normally as the bladder fills the detrusor is compliant - stretching and increasing the volume it holds - without any unpleasant sensation and the outlet is closed. At a socially acceptable time and place to void the bladder (detrusor) contracts and the outlet relaxes and flow ensues. Any perturbation in that balance can lead to voiding dysfunction or incontinence. Abnormal detrusor muscle activity or hypersensitivity of the bladder can lead to urge incontinence. An incompetent outlet can lead to stress incontinence. A bladder that cannot contract may lead to overflow incontinence.[1][2]

Urinary incontinence in children

Urination, or voiding, is a complex activity. The bladder is a balloon like muscle that lies in the lowest part of the abdomen. The bladder stores urine, then releases it through the urethra, the canal that carries urine to the outside of the body. Controlling this activity involves nerves, muscles, the spinal cord, and the brain.

The bladder is made of two types of muscles: the detrusor, a muscular sac that stores urine and squeezes to empty, and the sphincter, a circular group of muscles at the bottom or neck of the bladder that automatically stay contracted to hold the urine in and automatically relax when the detrusor contracts to let the urine into the urethra. A third group of muscles below the bladder (pelvic floor muscles) can contract to keep urine back.

A baby's bladder fills to a set point, then automatically contracts and empties. As the child gets older, the nervous system develops. The child's brain begins to get messages from the filling bladder and begins to send messages to the bladder to keep it from automatically emptying until the child decides it is the time and place to void.

Failures in this control mechanism result in incontinence. Reasons for this failure range from the simple to the complex.

Incontinence happens less often after age 5: About 10 percent of 5-year-olds, 5 percent of 10-year-olds, and 1 percent of 18-year-olds experience episodes of incontinence. It is twice as common in girls as in boys.

Incontinence is also called enuresis
  • Primary enuresis refers to wetting in a person who has never been dry for at least 6 months.
  • Secondary enuresis refers to wetting that begins after at least 6 months of dryness.
  • Nocturnal enuresis refers to wetting that usually occurs during sleep (nighttime incontinence).
  • Diurnal enuresis refers to wetting when awake (daytime incontinence).
Points to remember
  • Urinary incontinence in children is common.
  • Nighttime wetting occurs more commonly in boys.
  • Daytime Wetting is more common in girls.
  • After age 5, incontinence disappears naturally at a rate of 15 percent of cases per year.
  • Treatments include waiting, dietary modification, moisture alarms, medications, and bladder training.

References

  1. "pdfs.semanticscholar.org" (PDF).
  2. Brown JS, Bradley CS, Subak LL, Richter HE, Kraus SR, Brubaker L, Lin F, Vittinghoff E, Grady D (May 2006). "The sensitivity and specificity of a simple test to distinguish between urge and stress urinary incontinence". Ann. Intern. Med. 144 (10): 715–23. PMC 1557357. PMID 16702587.

Template:WH Template:WS