Typhus laboratory findings: Difference between revisions
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==Laboratory Findings== | ==Laboratory Findings== | ||
A diagnosis of rickettsial diseases is based on two or more of the following: | |||
* clinical symptoms and an epidemiologic history compatible with a rickettsial disease, | |||
* the development of specific convalescent-phase antibodies reactive with a given pathogen or antigenic group, | |||
* a positive polymerase chain reaction test result, | |||
* specific immunohistologic detection of rickettsial agent, | |||
* isolation of a rickettsial agent. Ascertaining the likely place and the nature of potential exposures is particularly helpful for accurate diagnostic testing. | |||
===Electrolyte and Biomarker Studies=== | ===Electrolyte and Biomarker Studies=== |
Revision as of 16:45, 12 December 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Laboratory Findings
A diagnosis of rickettsial diseases is based on two or more of the following:
- clinical symptoms and an epidemiologic history compatible with a rickettsial disease,
- the development of specific convalescent-phase antibodies reactive with a given pathogen or antigenic group,
- a positive polymerase chain reaction test result,
- specific immunohistologic detection of rickettsial agent,
- isolation of a rickettsial agent. Ascertaining the likely place and the nature of potential exposures is particularly helpful for accurate diagnostic testing.
Electrolyte and Biomarker Studies
A complete blood count (CBC) may show anemia and low platelets. Other blood tests for typhus may show:
- High level of typhus antibodies
- Low level of albumin
- Low sodium level
- Mild kidney failure
- Mildly high liver enzymes