Thyroid adenoma classification: Difference between revisions
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==Overview== | ==Overview== | ||
==Classification== | ==Classification== | ||
* Thyroid adenomas are classified into 2 subtype: follicular adenoma and others. | * Thyroid adenomas are classified into 2 subtype: [[Follicular thyroid adenoma|follicular adenoma]] and others. | ||
* | * Almost all [[thyroid]] adenomas are follicular adenomas.<ref name="isbn0-7216-0187-1">{{cite book |author=Cotran, Ramzi S.; Kumar, Vinay; Fausto, Nelson; Nelso Fausto; Robbins, Stanley L.; Abbas, Abul K. |title=Robbins and Cotran pathologic basis of disease |publisher=Elsevier Saunders |location=St. Louis, Mo |year=2005 |pages=1117 |isbn=0-7216-0187-1 |oclc= |doi= |accessdate=}}</ref> Others include papillary adenoma which is very rare.<ref name=Kelley2008>[http://emedicine.medscape.com/article/850823-overview#aw2aab6b4 emedicine > Thyroid, Evaluation of Solitary Thyroid Nodule > Benign Thyroid Nodules] By Daniel J Kelley and Arlen D Meyers. Updated: Oct 17, 2008</ref> | ||
* Follicular adenomas can be described as "cold", "warm" or "hot" depending on their level of function.<ref name="urlEndocrine Pathology">{{cite web |url=http://library.med.utah.edu/WebPath/ENDOHTML/ENDO037.html |title=Endocrine Pathology |format= |work= |accessdate=2009-05-08}}</ref> | * Follicular adenomas can be described as "cold", "warm" or "hot" depending on their level of function.<ref name="urlEndocrine Pathology">{{cite web |url=http://library.med.utah.edu/WebPath/ENDOHTML/ENDO037.html |title=Endocrine Pathology |format= |work= |accessdate=2009-05-08}}</ref> | ||
* [[Histopathological]]ly, follicular adenomas can be classified according to their cellular architecture and relative amounts of cellularity and colloid into the following types depicted in the flowchart. | * [[Histopathological]]ly, follicular adenomas can be classified according to their cellular architecture and relative amounts of cellularity and [[colloid]] into the following types depicted in the flowchart. | ||
{{Familytree/start}} | {{Familytree/start}} | ||
{{Familytree|boxstyle=background: #E0FFFF;| | | | | | | | | | | | | A01 | | | | | | | | | | | | | | | | | | |A01= Thyroid adenoma}} | {{Familytree|boxstyle=background: #E0FFFF;| | | | | | | | | | | | | A01 | | | | | | | | | | | | | | | | | | |A01= Thyroid adenoma}} | ||
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* Microfollicular adenoma (Fetal) | * Microfollicular adenoma (Fetal) | ||
| style="padding: 5px 5px; background: #F5F5F5;" | | | style="padding: 5px 5px; background: #F5F5F5;" | | ||
* Consist of small, closely packed follicles | * Consist of small, closely packed [[follicles]] | ||
* Have the potential for microinvasion | * Have the potential for [[microinvasion]] | ||
|- | |- | ||
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" | | | style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" | | ||
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* Macrofollicular adenoma (colloid adenoma) | * Macrofollicular adenoma (colloid adenoma) | ||
| style="padding: 5px 5px; background: #F5F5F5;" | | | style="padding: 5px 5px; background: #F5F5F5;" | | ||
* Consists of large amount of colloid | * Consists of large amount of [[colloid]] | ||
* Do not have the potential for microinvasion | * Do not have the potential for [[microinvasion]] | ||
|- | |- | ||
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" | | | style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" | | ||
| Line 42: | Line 42: | ||
* Hürthle cell adenoma (oxyphil or oncocytic tumor) | * Hürthle cell adenoma (oxyphil or oncocytic tumor) | ||
| style="padding: 5px 5px; background: #F5F5F5;" | | | style="padding: 5px 5px; background: #F5F5F5;" | | ||
* Consists of oxyphil cells | * Consists of [[oxyphil]] cells | ||
* Have the potential for microinvasion | * Have the potential for [[microinvasion]] | ||
|- | |- | ||
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" | | | style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" | | ||
4 | 4 | ||
| style="padding: 5px 5px; background: #F5F5F5;" | | | style="padding: 5px 5px; background: #F5F5F5;" | | ||
* Atypical embryonal adenoma | * Atypical embryonal adenoma | ||
| style="padding: 5px 5px; background: #F5F5F5;" | | | style="padding: 5px 5px; background: #F5F5F5;" | | ||
* Consists of embryonic cells | * Consists of embryonic cells | ||
* Have the potential for microinvasion | * Have the potential for [[microinvasion]] | ||
|- | |- | ||
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" | | | style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" | | ||
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* Hyalinizing trabecular adenoma | * Hyalinizing trabecular adenoma | ||
| style="padding: 5px 5px; background: #F5F5F5;" | | | style="padding: 5px 5px; background: #F5F5F5;" | | ||
* Consists of hyalinization | * Consists of [[hyalinization]] | ||
* Have the potential for microinvasion | * Have the potential for [[microinvasion]] | ||
|} | |} | ||
==Reference== | ==Reference== | ||
{{Reflist}} | {{Reflist}} | ||
Revision as of 05:06, 12 October 2015
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Thyroid adenoma Microchapters |
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Thyroid adenoma classification On the Web |
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Risk calculators and risk factors for Thyroid adenoma classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
Classification
- Thyroid adenomas are classified into 2 subtype: follicular adenoma and others.
- Almost all thyroid adenomas are follicular adenomas.[1] Others include papillary adenoma which is very rare.[2]
- Follicular adenomas can be described as "cold", "warm" or "hot" depending on their level of function.[3]
- Histopathologically, follicular adenomas can be classified according to their cellular architecture and relative amounts of cellularity and colloid into the following types depicted in the flowchart.
| Thyroid adenoma | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Microfollicular adenoma (fetal adenoma) | Macrofollicular adenoma (colloid adenoma) | Hürthle cell adenoma (oxyphil or oncocytic tumor) | Atypical embryonal adenoma | Hyalinizing trabecular adenoma | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
- Below is a table with the description of different types of follicular adenoma:[4]
| Number | Type of follicular adenoma | Description |
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1 |
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2 |
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3 |
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4 |
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5 |
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Reference
- ↑ Cotran, Ramzi S.; Kumar, Vinay; Fausto, Nelson; Nelso Fausto; Robbins, Stanley L.; Abbas, Abul K. (2005). Robbins and Cotran pathologic basis of disease. St. Louis, Mo: Elsevier Saunders. p. 1117. ISBN 0-7216-0187-1.
- ↑ emedicine > Thyroid, Evaluation of Solitary Thyroid Nodule > Benign Thyroid Nodules By Daniel J Kelley and Arlen D Meyers. Updated: Oct 17, 2008
- ↑ "Endocrine Pathology". Retrieved 2009-05-08.
- ↑ "TB Classification".