Thymoma natural history
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Natural history
Complications
Prognosis
Prognosis is much worse for stage III or IV thymomas as compared with stage I and II tumors. Invasive thymomas uncommonly can also metastasize, generally to pleura, bones, liver or brain in approximately 7% of cases.[1]
Patients with stage III and IV tumors may nonetheless survive for several years with appropriate oncological management.
Patients who have undergone thymectomy for thymoma should be warned of possible severe side effects after yellow fever vaccination. This is probably caused by inadequate T-cell response to live attenuated yellow fever vaccine. Deaths have been reported.
The prognosis of thymoma depends on the following:
- The location of the tumor.
- The stage of the tumor.
- Whether the tumor can be removed completely by surgery.
- The patient's general health.
- Whether the cancer has just been diagnosed or has recurred.
References
- ↑ Thomas CR, Wright CD, Loehrer PJ (1999). "Thymoma: state of the art". Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 17 (7): 2280–9. PMID 10561285. Text "accessdate" ignored (help); Unknown parameter
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