Thrombotic thrombocytopenic purpura surgery: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{CMG}}; {{AE}} {{S.G.}} | {{CMG}}; {{AE}} {{S.G.}} | ||
==Overview== | ==Overview== | ||
The mainstay of treatment for TTP is medical therapy. Surgery is usually reserved for patients with either no cure with plasma treatments and medicines. | The mainstay of treatment for TTP is [[medical]] [[therapy]]. [[Surgery]] is usually reserved for [[Patient|patients]] with either no [[cure]] with [[plasma]] [[Treatment|treatments]] and medicines. | ||
==Indications== | ==Indications== | ||
*Surgery is not the first | *[[Surgery]] is not the [[First-line treatment|first line treatment]] option for [[Patient|patients]] withTTP when [[plasma]] treatments(PEX) and medicines do not [[cure]] TTP, [[surgery]] is needed.<ref name="pmid11604563">{{cite journal |vauthors=Medina PJ, Sipols JM, George JN |title=Drug-associated thrombotic thrombocytopenic purpura-hemolytic uremic syndrome |journal=Curr. Opin. Hematol. |volume=8 |issue=5 |pages=286–93 |date=September 2001 |pmid=11604563 |doi= |url=}}</ref> | ||
==Surgery== | ==Surgery== | ||
*Surgery is not the first-line treatment option for patients withTTP. Sometimes | *[[Surgery]] is not the [[first-line treatment]] option for [[Patient|patients]] withTTP. Sometimes [[splenectomy]] is needed, because the [[antibodies]] is made by [[Cell (biology)|cell]] in [[spleen]] that block [[ADAMTS13]] [[enzyme]] [[Activity (chemistry)|activity]].<ref name="pmid11604563" /> | ||
==References== | ==References== | ||
Revision as of 16:31, 5 October 2018
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sogand Goudarzi, MD [2]
Overview
The mainstay of treatment for TTP is medical therapy. Surgery is usually reserved for patients with either no cure with plasma treatments and medicines.
Indications
- Surgery is not the first line treatment option for patients withTTP when plasma treatments(PEX) and medicines do not cure TTP, surgery is needed.[1]
Surgery
- Surgery is not the first-line treatment option for patients withTTP. Sometimes splenectomy is needed, because the antibodies is made by cell in spleen that block ADAMTS13 enzyme activity.[1]