Template:Lipid signaling: Difference between revisions

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Latest revision as of 07:46, 10 January 2019

Cell signaling: lipid signaling

Extracellular

Eicosanoids	Classic: Eoxins; Leukotrienes (LTR) Prostacyclin (IPR) Prostaglandins (PGR) Thromboxane (TXR) Nonclassic: EETs Endocannabinoids (CBR) Epi-lipoxins (FPR2) Hepoxilins Isoprostanes Lipoxins (FPR2) Oxoeicosanoids (OXER) Resolvins (FPR2)
Lysophospholipids	LPA (LPAR) S1P (S1PR)
Steroids	Bile acids (GPBAR) Neurosteroids Pheromones (VNR)
Others	PAF (PAFR) Retinal (RHO)

Intracellular

Nuclear receptor	Steroids: Sex steroids: Androgens (AR) Estrogens (ER) Progestogens (PR); Corticosteroids: Glucocorticoids (GR) Mineralocorticoids (MR); Others: Bile acids (FXR) Calcitriol (VDR); Others: Eicosanoids (PPAR) Free fatty acids (PPAR) Retinoic acid (RAR, RXR)
Second messenger	General: Arachidonic acid DAG (PKC, TRPC) IP₃ (IP₃R, RyR) Phosphatidic acid Phosphoinositides: PIP₂ (IRKs) PIP₃ (PKB/Akt, Btk, PDPK1) PtdIns(3,4)P₂ (PKB/Akt, PDPK1); Sphingolipids: C1P Ceramide (CAPPs, KSR1, PKCζ, CTSD) Glucosylceramides S1P Sphingosine (SDK1, PKH, YPK)

Precursors

General	Fatty acids (ω-3, ω-6)
Steroids	Squalene Lanosterol Cholesterol

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