TIMI thrombus grade 6
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Rim Halaby, M.D. [2]
Overview
In PERFUSE Grade 6 thrombus, a chronic total occlusion is present.[1]
The characteristics of a chronic total occlusion are:
- The occlusion does not have a "beak like" appearance, and the occlusion has a blunt cut-off/edge.
- Extensive collaterals may be present.
- The clot generally propagates backwards up the proximal vessel to the nearest proximal side branch.
Example
Shown below are an animated image an a static image depicting PERFUSE grade 6 thrombus in the left circumflex. Encircled in yellow in the image on the right is the thrombus, where you can notice an abrupt blunt cut-off appearance. Outlined in yellow in the same image on the right is the path of the dye in a collateral artery arising from the LAD.
Shown below are two animated images of the same case depicting PERFUSE grade 6 thrombus in the left circumflex. The image on the left shows the same thrombus before PCI and the image on the left shows the patent left circumflex after PCI.
Additional Examples
Click here for other examples on PERFUSE thrombus grade 6.
References
- ↑ Gibson CM, de Lemos JA, Murphy SA, Marble SJ, McCabe CH, Cannon CP; et al. (2001). "Combination therapy with abciximab reduces angiographically evident thrombus in acute myocardial infarction: a TIMI 14 substudy". Circulation. 103 (21): 2550–4. PMID 11382722.