Synergy Between Percutaneous Coronary Intervention With Taxus and Cardiac Surgery
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Associate Editor-In-Chief: Atif Mohammad, M.D.
Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [2] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.
Related Key Words and Synonyms:
Overview
SYNTAX which is the abbreviation for "Synergy between Percutaneous Coronary Intervention with Taxus and Cardiac Surgery" was a prospective clinical trial conducted in 85 sites in 17 countries across Europe and the United States.The purpose of this study was to assess objective revascularization strategy and treatment protocol for patients with previously untreated 3-vessel disease or left main coronary artery disease and identify the populations for whom only one will be better.Previous clinical trials comparing bare metal stents with CABG have shown similar survival rates but higher revascularization rates in patients having bare metal stents. Randomized clinical trials have also shown Drug Eluting Stents (DES)as compared with Bare Metal Stents (BMS), to show better results in terms of repeat revascularization, myocardial infarction and deaths especially in more complex anatomical cases .The SYNTAX trial was conducted to assess the efficacy of Taxus which is a Paclitaxel coated drug eluting stent as compared to CABG for effective means of revascularization in patients with three vessel disease or left main disease.