Strep throat natural history: Difference between revisions

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__NOTOC__
__NOTOC__
{{Strep throat}}
{{Strep throat}}
{{CMG}}{{AE}}{{AA}}
{{CMG}}; {{AE}} {{TarekNafee}}; {{AA}}
==Overview==
==Overview==
If left untreated, group A streptococcal pharngitis is usually self limited. However, it is more likely to develop complications such as peritonsillar abscess, mastoiditis and acute rheumatic fever in untreated cases.<ref name=cdcp>http://www.cdc.gov/groupastrep/diseases-hcp/strep-throat.html Accessed on October 18, 2016</ref><ref name="pmid18731131">{{cite journal| author=Rantz LA| title=THE NATURAL HISTORY OF HEMOLYTIC STREPTOCOCCUS SORE THROAT. | journal=Calif Med | year= 1946 | volume= 65 | issue= 6 | pages= 265-70 | pmid=18731131 | doi= | pmc=1642726 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18731131  }} </ref><ref name="pmid21965709">{{cite journal| author=Langlois DM, Andreae M| title=Group A streptococcal infections. | journal=Pediatr Rev | year= 2011 | volume= 32 | issue= 10 | pages= 423-9; quiz 430 | pmid=21965709 | doi=10.1542/pir.32-10-423 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21965709  }} </ref>
If left untreated, group A streptococcal [[pharyngitis]] may be self-limiting. In some cases, complications such as [[peritonsillar abscess]], [[retropharyngeal abscess]], [[mastoiditis]], and [[Lymphadenitis|cervical lymphadenitis]] may develop in untreated patients.<ref name="cdcp">http://www.cdc.gov/groupastrep/diseases-hcp/strep-throat.html Accessed on October 18, 2016</ref><ref name="pmid18731131">{{cite journal| author=Rantz LA| title=THE NATURAL HISTORY OF HEMOLYTIC STREPTOCOCCUS SORE THROAT. | journal=Calif Med | year= 1946 | volume= 65 | issue= 6 | pages= 265-70 | pmid=18731131 | doi= | pmc=1642726 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18731131  }} </ref><ref name="pmid21965709">{{cite journal| author=Langlois DM, Andreae M| title=Group A streptococcal infections. | journal=Pediatr Rev | year= 2011 | volume= 32 | issue= 10 | pages= 423-9; quiz 430 | pmid=21965709 | doi=10.1542/pir.32-10-423 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21965709  }} </ref> Less commonly, [[post-streptococcal glomerulonephritis]],  [[Rheumatic fever|rheumatic fever,]] and [[toxic shock syndrome]] may develop as delayed complications. Rarely, [[vasculitis]] may occur. The [[prognosis]] of strep throat is good with treatment; complications rarely develop with adequate treatment.


==Natural history==  
==Natural history==  
If left untreated, group A streptococcal pharngitis is usually self limited. However, it is more likely to develop complications such as peritonsillar abscess, mastoiditis and acute rheumatic fever in untreated cases.<ref name=cdcp>http://www.cdc.gov/groupastrep/diseases-hcp/strep-throat.html Accessed on October 18, 2016</ref><ref name="pmid18731131">{{cite journal| author=Rantz LA| title=THE NATURAL HISTORY OF HEMOLYTIC STREPTOCOCCUS SORE THROAT. | journal=Calif Med | year= 1946 | volume= 65 | issue= 6 | pages= 265-70 | pmid=18731131 | doi= | pmc=1642726 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18731131  }} </ref>
If left untreated, group A streptococcal [[pharyngitis]] may be self-limiting. In some cases, complications such as [[peritonsillar abscess]], [[retropharyngeal abscess]], [[mastoiditis]], and [[Lymphadenitis|cervical lymphadenitis]] may develop in untreated patients which may results in [[septic shock]] or death if they are not managed appropriately.<ref name="cdcp" /><ref name="pmid18731131" /><ref name="pmid21965709" /> Less commonly, delayed chronic complications such as [[post-streptococcal glomerulonephritis]],  [[Rheumatic fever|rheumatic fever,]] and [[toxic shock syndrome]] may develop. Rarely, [[vasculitis]] may occur.


==Complications==
==Complications==
Complications that can develop as a result of strep throat may be divided into suppurative and non suppurative types:<ref name=cdcp>http://www.cdc.gov/groupastrep/diseases-hcp/strep-throat.html Accessed on October 18, 2016</ref><ref name="pmid21965709">{{cite journal| author=Langlois DM, Andreae M| title=Group A streptococcal infections. | journal=Pediatr Rev | year= 2011 | volume= 32 | issue= 10 | pages= 423-9; quiz 430 | pmid=21965709 | doi=10.1542/pir.32-10-423 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21965709  }} </ref>
Complications that can develop as a result of strep throat may be divided into [[suppurative]] and non-suppurative types:<ref name="cdcp">http://www.cdc.gov/groupastrep/diseases-hcp/strep-throat.html Accessed on October 18, 2016</ref><ref name="pmid21965709">{{cite journal| author=Langlois DM, Andreae M| title=Group A streptococcal infections. | journal=Pediatr Rev | year= 2011 | volume= 32 | issue= 10 | pages= 423-9; quiz 430 | pmid=21965709 | doi=10.1542/pir.32-10-423 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21965709  }} </ref>
===Suppurative===
===Suppurative===
*[[Peritonsillar abscess]]
*[[Peritonsillar abscess]]
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*[[Otitis media]]
*[[Otitis media]]
*[[Sinusitis]]
*[[Sinusitis]]
*Cervical lymphadenitis
*Cervical [[lymphadenitis]]
*[[Mastoiditis]]
*[[Mastoiditis]]
*[[Vasculitis]]
'''Images of [[vasculitis]] after Streptococcal throat infection'''


===Non suppurative ===
[[File:Strep vasculitis 1.jpg|Streptococcal vasculitis|left|thumb|300px| Case courtesy of wikidoc.org]]
[[File:Strep vasculitis 2.jpg|Streptococcal vasculitis|left|thumb|300px| Case courtesy of wikidoc.org]]
<br style="clear:left" />
 
===Non-suppurative ===
*[[Rheumatic fever]]
*[[Rheumatic fever]]
*[[Acute glomerulonephritis]]
*[[Acute glomerulonephritis]]
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==Prognosis==
==Prognosis==
The [[prognosis]] of Strep throat is good with treatment. Complications rarely develops with adequate treatment.<ref name=cdcp>http://www.cdc.gov/groupastrep/diseases-hcp/strep-throat.html Accessed on October 18, 2016</ref>
The [[prognosis]] of strep throat is good with treatment. Complications rarely develop with adequate treatment.<ref name="cdcp">http://www.cdc.gov/groupastrep/diseases-hcp/strep-throat.html Accessed on October 18, 2016</ref>


==References==
==References==
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{{WH}}
{{WH}}
{{WS}}
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[[Category:Emergency mdicine]]
[[Category:Disease]]
[[Category:Up-To-Date]]
[[Category:Infectious disease]]
[[Category:Pediatrics]]
[[Category:Otolaryngology]]

Latest revision as of 00:19, 30 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Tarek Nafee, M.D. [2]; Aysha Anwar, M.B.B.S[3]

Overview

If left untreated, group A streptococcal pharyngitis may be self-limiting. In some cases, complications such as peritonsillar abscess, retropharyngeal abscess, mastoiditis, and cervical lymphadenitis may develop in untreated patients.[1][2][3] Less commonly, post-streptococcal glomerulonephritis, rheumatic fever, and toxic shock syndrome may develop as delayed complications. Rarely, vasculitis may occur. The prognosis of strep throat is good with treatment; complications rarely develop with adequate treatment.

Natural history

If left untreated, group A streptococcal pharyngitis may be self-limiting. In some cases, complications such as peritonsillar abscess, retropharyngeal abscess, mastoiditis, and cervical lymphadenitis may develop in untreated patients which may results in septic shock or death if they are not managed appropriately.[1][2][3] Less commonly, delayed chronic complications such as post-streptococcal glomerulonephritis, rheumatic fever, and toxic shock syndrome may develop. Rarely, vasculitis may occur.

Complications

Complications that can develop as a result of strep throat may be divided into suppurative and non-suppurative types:[1][3]

Suppurative

Images of vasculitis after Streptococcal throat infection

Case courtesy of wikidoc.org
Case courtesy of wikidoc.org


Non-suppurative

Prognosis

The prognosis of strep throat is good with treatment. Complications rarely develop with adequate treatment.[1]

References

  1. 1.0 1.1 1.2 1.3 http://www.cdc.gov/groupastrep/diseases-hcp/strep-throat.html Accessed on October 18, 2016
  2. 2.0 2.1 Rantz LA (1946). "THE NATURAL HISTORY OF HEMOLYTIC STREPTOCOCCUS SORE THROAT". Calif Med. 65 (6): 265–70. PMC 1642726. PMID 18731131.
  3. 3.0 3.1 3.2 Langlois DM, Andreae M (2011). "Group A streptococcal infections". Pediatr Rev. 32 (10): 423–9, quiz 430. doi:10.1542/pir.32-10-423. PMID 21965709.


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