Squamous cell carcinoma of the lung staging

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shanshan Cen, M.D. [2] Maria Fernanda Villarreal, M.D. [3]

Overview

According to the American Joint Committee on Cancer (AJCC) staging system, TNM system classifies squamous cell carcinoma of the lung by 3 factors, T for tumor, N for nodes, M for metastasis.[1]

Staging

American Joint Committee on Cancer (AJCC) Staging

  • The table below summarizes the TNM staging system for the diagnosis of non-small cell lung cancer[1]
TNM Description
TX The primary tumour cannot be assessed, or there are malignant cells in the sputum or bronchoalveolar lavage but not seen on imaging or bronchoscopy
T0 No evidence of primary tumor
Tis Carcinoma in situ
T1 Tumour less than 3 cm in its greatest dimension, surrounded by lung or visceral pleura and without bronchoscopic invasion into the main bronchus.
T2 A tumour with any of: more than 3 cm in greatest dimension; Extending into the main bronchus, but more than 2 cm distal to the carina; Obstructive pneumonitis, but not involving the entire lung
T3 A tumour with any of: invasion of the chest wall, diaphragm, mediastinal pleura, or parietal pericardium; Extending into the main bronchus, within 2 cm of the carina, but not involving the carina; Obstructive pneumonitis of the entire lung
T4 A tumour with any of: invasion of the mediastinum, heart, great vessels, trachea, oesophagus, vertebra, or carina; Separate tumour nodules in the same lobe; Malignant pleural effusion
Regional Lymph Nodes
NX Lymph nodes cannot be assessed
N0 No lymph nodes involved
N1 Metastasis to ipsilateral peribronchial or ipsilateral hilar lymph nodes
N2 Metastasis to ipsilateral mediastinal or subcarinal lymph nodes
N3 Metastasis to any of: ipsilateral supraclavicular lymph nodes; Ipsilateral scalene lymph nodes; Contralateral lymph nodes.
Distant Metastasis
MX Distant metastasis cannot be assessed
M0 No distant metastasis
M1 Distant metastasis is present


References

  1. 1.0 1.1 Stages of non–small cell lung cancer. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/lung/staging/?region=ab


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