Squamous cell carcinoma of the lung staging: Difference between revisions

Jump to navigation Jump to search
VisualWikitext
No edit summary
No edit summary
Line 1: Line 1:
__NOTOC__
__NOTOC__
{{Squamous cell carcinoma of the lung}}
{{Squamous cell carcinoma of the lung}}
{{CMG}}; {{AE}} {{SC}}
{{CMG}}; {{AE}} {{SC}} {{MV}}
==Overview==
==Overview==
Squamous cell carcinoma of the lung may be classified into several subtypes based on [[TNM]] and [[UICC]] staging system.<ref name=canadian>Stages of non–small cell lung cancer. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/lung/staging/?region=ab</ref>
 
According to the [[American Joint Committee on Cancer|American Joint Committee on Cancer (AJCC)]] staging system, TNM system classifies squamous cell carcinoma of the lung by 3 factors, T for tumor, N for nodes, M for metastasis.<ref name="canadian">Stages of non–small cell lung cancer. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/lung/staging/?region=ab</ref>


==Staging==
==Staging==
'''TNM staging'''<ref name=canadian>Stages of non–small cell lung cancer. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/lung/staging/?region=ab</ref>
 
===American Joint Committee on Cancer (AJCC) Staging===
*The table below summarizes the TNM staging system for the diagnosis of non-small cell lung cancer<ref name=canadian>Stages of non–small cell lung cancer. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/lung/staging/?region=ab</ref>
{| style="border: 0px; font-size: 90%; margin: 3px; width: 600px" align=center
{| style="border: 0px; font-size: 90%; margin: 3px; width: 600px" align=center
|valign=top|
|valign=top|
|+
|+
! style="background: #4479BA; width: 100px;" | {{fontcolor|#FFF|TNM}}
! style="background: #4479BA; width: 100px;" | {{fontcolor|#FFF|TNM}}
! style="background: #4479BA; width: 400px;" | {{fontcolor|#FFF| Definition}}
! style="background: #4479BA; width: 400px;" | {{fontcolor|#FFF|Description}}
|-
|-
| style="padding: 5px 5px; background: #DCDCDC;" |TX
| style="padding: 5px 5px; background: #DCDCDC;" |TX
| style="padding: 5px 5px; background: #F5F5F5;" |The primary [[tumour]] cannot be assessed, or there are [[malignant]] [[cell (biology)|cells]] in the [[sputum]] or [[bronchoalveolar lavage]] but not seen on imaging or [[bronchoscopy]].
| style="padding: 5px 5px; background: #F5F5F5;" |The primary [[tumour]] cannot be assessed, or there are [[malignant]] [[cell (biology)|cells]] in the [[sputum]] or [[bronchoalveolar lavage]] but not seen on imaging or [[bronchoscopy]]
|-
|-
| style="padding: 5px 5px; background: #DCDCDC;" |T0
| style="padding: 5px 5px; background: #DCDCDC;" |T0
| style="padding: 5px 5px; background: #F5F5F5;" |No evidence of primary tumor.
| style="padding: 5px 5px; background: #F5F5F5;" |No evidence of primary tumor
|-
|-
| style="padding: 5px 5px; background: #DCDCDC;" |Tis
| style="padding: 5px 5px; background: #DCDCDC;" |Tis
| style="padding: 5px 5px; background: #F5F5F5;" |[[Carcinoma in situ]].
| style="padding: 5px 5px; background: #F5F5F5;" |[[Carcinoma in situ]]
|-
| style="padding: 5px 5px; background: #DCDCDC;" rowspan=3|T1
| style="padding: 5px 5px; background: #F5F5F5;" |Tumour is 3 cm or less in size and has not spread to the visceral pleura or the main bronchi.
|-
| style="padding: 5px 5px; background: #F5F5F5;" |T1a – Tumour is smaller than 2 cm.
|-
| style="padding: 5px 5px; background: #F5F5F5;" |T1b – Tumour is larger than 2 cm, but smaller than 3 cm.
|-
| style="padding: 5px 5px; background: #DCDCDC;" rowspan=3 |T2
| style="padding: 5px 5px; background: #F5F5F5;" |Tumour is larger than 3 cm, but smaller than 7 cm; or the tumour has any of the following features: Cancer has spread to the main bronchi, but is not closer than 2 cm to the carina; Cancer has spread to the visceral pleura; Tumour is associated with obstructive pneumonitis or atelectasis.
|-
|-
| style="padding: 5px 5px; background: #F5F5F5;" |T2a – Tumour is larger than 3 cm, but 5 cm or less in size.
| style="padding: 5px 5px; background: #DCDCDC;" |T1
| style="padding: 5px 5px; background: #F5F5F5;" |Tumour less than 3 cm in its greatest dimension, surrounded by [[lung]] or visceral [[pleura]] and without bronchoscopic invasion into the main [[bronchus]].
|-
|-
| style="padding: 5px 5px; background: #F5F5F5;" |T2b – Tumour is larger than 5 cm, but 7 cm or less in size
| style="padding: 5px 5px; background: #DCDCDC;" |T2
| style="padding: 5px 5px; background: #F5F5F5;" |A tumour with any of: more than 3 cm in greatest dimension; Extending into the main bronchus, but more than 2 cm distal to the [[Carina (anatomy)|carina]]; Obstructive [[pneumonitis]], but not involving the entire lung
|-
|-
| style="padding: 5px 5px; background: #DCDCDC;" |T3
| style="padding: 5px 5px; background: #DCDCDC;" |T3
| style="padding: 5px 5px; background: #F5F5F5;" |A tumour with any of: Invasion of the chest wall, [[Thoracic diaphragm|diaphragm]], [[mediastinum|mediastinal]] pleura, or parietal [[pericardium]]; Extending into the main bronchus, within 2 cm of the carina, but not involving the carina; Obstructive pneumonitis of the entire lung.
| style="padding: 5px 5px; background: #F5F5F5;" |A tumour with any of: invasion of the chest wall, [[Thoracic diaphragm|diaphragm]], [[mediastinum|mediastinal]] pleura, or parietal [[pericardium]]; Extending into the main bronchus, within 2 cm of the carina, but not involving the carina; Obstructive pneumonitis of the entire lung
|-
|-
| style="padding: 5px 5px; background: #DCDCDC;" |T4
| style="padding: 5px 5px; background: #DCDCDC;" |T4
| style="padding: 5px 5px; background: #F5F5F5;" |A tumour with any of: Invasion of the mediastinum, [[heart]], great vessels, [[Vertebrate trachea|trachea]], [[oesophagus]], [[vertebra]], or carina; Separate tumour nodules in the same lobe; Malignant [[pleural effusion]].
| style="padding: 5px 5px; background: #F5F5F5;" |A tumour with any of: invasion of the mediastinum, [[heart]], great vessels, [[Vertebrate trachea|trachea]], [[oesophagus]], [[vertebra]], or carina; Separate tumour nodules in the same lobe; Malignant [[pleural effusion]]
|-
|-
| style="padding: 0 5px; background: #4479BA" colspan=3 |{{fontcolor|#FFF| Regional Lymph Nodes}}
| style="padding: 0 5px; background: #4479BA" colspan=3 |{{fontcolor|#FFF| Regional Lymph Nodes}}
|-
|-
| style="padding: 5px 5px; background: #DCDCDC;" |NX
| style="padding: 5px 5px; background: #DCDCDC;" |NX
| style="padding: 5px 5px; background: #F5F5F5;" |[[Lymph node]]s cannot be assessed.
| style="padding: 5px 5px; background: #F5F5F5;" |[[Lymph node]]s cannot be assessed
|-
|-
| style="padding: 5px 5px; background: #DCDCDC;" |N0
| style="padding: 5px 5px; background: #DCDCDC;" |N0
| style="padding: 5px 5px; background: #F5F5F5;" |No lymph nodes involved.
| style="padding: 5px 5px; background: #F5F5F5;" |No lymph nodes involved
|-
|-
| style="padding: 5px 5px; background: #DCDCDC;" |N1
| style="padding: 5px 5px; background: #DCDCDC;" |N1
| style="padding: 5px 5px; background: #F5F5F5;" |[[Metastasis]] to [[ipsilateral]] peribronchial or ipsilateral hilar lymph nodes.
| style="padding: 5px 5px; background: #F5F5F5;" |[[Metastasis]] to [[ipsilateral]] peribronchial or ipsilateral hilar lymph nodes
|-
|-
| style="padding: 5px 5px; background: #DCDCDC;" |N2
| style="padding: 5px 5px; background: #DCDCDC;" |N2
| style="padding: 5px 5px; background: #F5F5F5;" |Metastasis to ipsilateral mediastinal or subcarinal lymph nodes.
| style="padding: 5px 5px; background: #F5F5F5;" |Metastasis to ipsilateral mediastinal or subcarinal lymph nodes
|-
|-
| style="padding: 5px 5px; background: #DCDCDC;" |N3
| style="padding: 5px 5px; background: #DCDCDC;" |N3
| style="padding: 5px 5px; background: #F5F5F5;" |Metastasis to any of: Ipsilateral supraclavicular lymph nodes; Ipsilateral scalene lymph nodes; [[Contralateral]] lymph nodes.
| style="padding: 5px 5px; background: #F5F5F5;" |Metastasis to any of: ipsilateral supraclavicular lymph nodes; Ipsilateral scalene lymph nodes; [[Contralateral]] lymph nodes.
|-|-
|-|-
| style="padding: 0 5px; background: #4479BA" colspan=3 |{{fontcolor|#FFF| Distant Metastasis}}
| style="padding: 0 5px; background: #4479BA" colspan=3 |{{fontcolor|#FFF| Distant Metastasis}}
|-
| style="padding: 5px 5px; background: #DCDCDC;" |MX
| style="padding: 5px 5px; background: #F5F5F5;" |Distant metastasis cannot be assessed
|-
|-
| style="padding: 5px 5px; background: #DCDCDC;" |M0
| style="padding: 5px 5px; background: #DCDCDC;" |M0
| style="padding: 5px 5px; background: #F5F5F5;" |No distant metastasis.
| style="padding: 5px 5px; background: #F5F5F5;" |No distant metastasis
|-
| style="padding: 5px 5px; background: #DCDCDC;" rowspan=3|M1
| style="padding: 5px 5px; background: #F5F5F5;" |Distant metastasis is present.
|-
| style="padding: 5px 5px; background: #F5F5F5;" |M1a – Any one of the following: Separate tumour nodule(s) in the opposite lung; Tumour nodules on the parietal pleura; Pleural effusion or pericardial effusion.
|-
|-
| style="padding: 5px 5px; background: #F5F5F5;" |M1b – Distant metastasis.
| style="padding: 5px 5px; background: #DCDCDC;" |M1
| style="padding: 5px 5px; background: #F5F5F5;" |Distant metastasis is present
|}
|}


'''UICC staging'''<ref name=canadian>Stages of non–small cell lung cancer. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/lung/staging/?region=ab</ref>
{| style="border: 0px; font-size: 90%; margin: 3px; width: 600px" align=center
|valign=top|
|+
! style="background: #4479BA; width: 100px;" | {{fontcolor|#FFF|Stage}}
! style="background: #4479BA; width: 100px;" | {{fontcolor|#FFF| T}}
! style="background: #4479BA; width: 100px;" | {{fontcolor|#FFF| N}}
! style="background: #4479BA; width: 100px;" | {{fontcolor|#FFF| M}}
|-
| style="padding: 5px 5px; background: #DCDCDC;" |Occult carcinoma
| style="padding: 5px 5px; background: #F5F5F5;" |TX
| style="padding: 5px 5px; background: #F5F5F5;" |N0
| style="padding: 5px 5px; background: #F5F5F5;" |M0
|-
| style="padding: 5px 5px; background: #DCDCDC;" |Stage 0
| style="padding: 5px 5px; background: #F5F5F5;" |Tis
| style="padding: 5px 5px; background: #F5F5F5;" |N0
| style="padding: 5px 5px; background: #F5F5F5;" |M0
|-
| style="padding: 5px 5px; background: #DCDCDC;" |Stage IA
| style="padding: 5px 5px; background: #F5F5F5;" |T1
| style="padding: 5px 5px; background: #F5F5F5;" |N0
| style="padding: 5px 5px; background: #F5F5F5;" |M0
|-
| style="padding: 5px 5px; background: #DCDCDC;" |Stage IB
| style="padding: 5px 5px; background: #F5F5F5;" |T2a
| style="padding: 5px 5px; background: #F5F5F5;" |N0
| style="padding: 5px 5px; background: #F5F5F5;" |M0
|-
| style="padding: 5px 5px; background: #DCDCDC;" rowspan=3 |Stage IIA
| style="padding: 5px 5px; background: #F5F5F5;" |T2b
| style="padding: 5px 5px; background: #F5F5F5;" |N0
| style="padding: 5px 5px; background: #F5F5F5;" |M0
|-
| style="padding: 5px 5px; background: #F5F5F5;" |T1
| style="padding: 5px 5px; background: #F5F5F5;" |N1
| style="padding: 5px 5px; background: #F5F5F5;" |M0
|-
| style="padding: 5px 5px; background: #F5F5F5;" |T2a
| style="padding: 5px 5px; background: #F5F5F5;" |N1
| style="padding: 5px 5px; background: #F5F5F5;" |M0
|-
| style="padding: 5px 5px; background: #DCDCDC;" rowspan="2"|Stage IIB
| style="padding: 5px 5px; background: #F5F5F5;" |T2b
| style="padding: 5px 5px; background: #F5F5F5;" |N1
| style="padding: 5px 5px; background: #F5F5F5;" |M0
|-
| style="padding: 5px 5px; background: #F5F5F5;" |T3
| style="padding: 5px 5px; background: #F5F5F5;" |N0
| style="padding: 5px 5px; background: #F5F5F5;" |M0
|-
| style="padding: 5px 5px; background: #DCDCDC;" rowspan=6|Stage IIIA
| style="padding: 5px 5px; background: #F5F5F5;" |T1
| style="padding: 5px 5px; background: #F5F5F5;" |N2
| style="padding: 5px 5px; background: #F5F5F5;" |M0
|-
| style="padding: 5px 5px; background: #F5F5F5;" |T2
| style="padding: 5px 5px; background: #F5F5F5;" |N2
| style="padding: 5px 5px; background: #F5F5F5;" |M0
|-
| style="padding: 5px 5px; background: #F5F5F5;" |T3
| style="padding: 5px 5px; background: #F5F5F5;" |N1
| style="padding: 5px 5px; background: #F5F5F5;" |M0
|-
| style="padding: 5px 5px; background: #F5F5F5;" |T3
| style="padding: 5px 5px; background: #F5F5F5;" |N2
| style="padding: 5px 5px; background: #F5F5F5;" |M0
|-
| style="padding: 5px 5px; background: #F5F5F5;" |T4
| style="padding: 5px 5px; background: #F5F5F5;" |N0
| style="padding: 5px 5px; background: #F5F5F5;" |M0
|-
| style="padding: 5px 5px; background: #F5F5F5;" |T4
| style="padding: 5px 5px; background: #F5F5F5;" |N1
| style="padding: 5px 5px; background: #F5F5F5;" |M0
|-
| style="padding: 5px 5px; background: #DCDCDC;" rowspan="2"|Stage IIIB
| style="padding: 5px 5px; background: #F5F5F5;" |T4
| style="padding: 5px 5px; background: #F5F5F5;" |N2
| style="padding: 5px 5px; background: #F5F5F5;" |M0
|-
| style="padding: 5px 5px; background: #F5F5F5;" |Any T   
| style="padding: 5px 5px; background: #F5F5F5;" |N3
| style="padding: 5px 5px; background: #F5F5F5;" |M0
|-
| style="padding: 5px 5px; background: #DCDCDC;" |Stage IV
| style="padding: 5px 5px; background: #F5F5F5;" |Any T 
| style="padding: 5px 5px; background: #F5F5F5;" |Any N
| style="padding: 5px 5px; background: #F5F5F5;" |M1
|}


==References==
==References==

Revision as of 16:46, 4 March 2016

Squamous Cell Carcinoma of the Lung Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Squamous Cell Carcinoma of the Lung from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic study of choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X-ray

Echocardiography and Ultrasound

CT scan

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Squamous cell carcinoma of the lung staging On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Squamous cell carcinoma of the lung staging

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Squamous cell carcinoma of the lung staging

CDC on Squamous cell carcinoma of the lung staging

Squamous cell carcinoma of the lung staging in the news

Blogs on Squamous cell carcinoma of the lung staging

Directions to Hospitals Treating Squamous cell carcinoma of the lung

Risk calculators and risk factors for Squamous cell carcinoma of the lung staging

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shanshan Cen, M.D. [2] Maria Fernanda Villarreal, M.D. [3]

Overview

According to the American Joint Committee on Cancer (AJCC) staging system, TNM system classifies squamous cell carcinoma of the lung by 3 factors, T for tumor, N for nodes, M for metastasis.[1]

Staging

American Joint Committee on Cancer (AJCC) Staging

  • The table below summarizes the TNM staging system for the diagnosis of non-small cell lung cancer[1]
TNM Description
TX The primary tumour cannot be assessed, or there are malignant cells in the sputum or bronchoalveolar lavage but not seen on imaging or bronchoscopy
T0 No evidence of primary tumor
Tis Carcinoma in situ
T1 Tumour less than 3 cm in its greatest dimension, surrounded by lung or visceral pleura and without bronchoscopic invasion into the main bronchus.
T2 A tumour with any of: more than 3 cm in greatest dimension; Extending into the main bronchus, but more than 2 cm distal to the carina; Obstructive pneumonitis, but not involving the entire lung
T3 A tumour with any of: invasion of the chest wall, diaphragm, mediastinal pleura, or parietal pericardium; Extending into the main bronchus, within 2 cm of the carina, but not involving the carina; Obstructive pneumonitis of the entire lung
T4 A tumour with any of: invasion of the mediastinum, heart, great vessels, trachea, oesophagus, vertebra, or carina; Separate tumour nodules in the same lobe; Malignant pleural effusion
Regional Lymph Nodes
NX Lymph nodes cannot be assessed
N0 No lymph nodes involved
N1 Metastasis to ipsilateral peribronchial or ipsilateral hilar lymph nodes
N2 Metastasis to ipsilateral mediastinal or subcarinal lymph nodes
N3 Metastasis to any of: ipsilateral supraclavicular lymph nodes; Ipsilateral scalene lymph nodes; Contralateral lymph nodes.
Distant Metastasis
MX Distant metastasis cannot be assessed
M0 No distant metastasis
M1 Distant metastasis is present


References

  1. ↑ 1.0 1.1 Stages of non–small cell lung cancer. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/lung/staging/?region=ab


Template:WikiDoc Sources

Retrieved from "https://www.wikidoc.org/index.php?title=Squamous_cell_carcinoma_of_the_lung_staging&oldid=1222402"