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{{Squamous cell carcinoma of the lung}}
{{Squamous cell carcinoma of the lung}}
{{CMG}}; {{AE}} {{MV}}
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==Overview==
==Overview==
Squamous cell carcinoma of the lung may be classified according to the [[World Health Organization|WHO histological classification system]] into 4 main types: papillary, clear cell, small cell, and basaloid.
Squamous cell carcinoma of the lung may be classified according to the [[World Health Organization|WHO histological classification system]] into 4 main types: Keratinizing squamous cell carcinoma, nonkeratinizing squamous cell carcinoma, basaloid squamous cell carcinoma and preinvasive lesion.


==Classification==
==WHO Histological Classification==
* There are 4 main types of squamous cell carcinoma of the lung:<ref name="NSCLC">Non-Small Cell Lung Cancer Treatment –for health professionals. National Cancer Institute – Physician Data Query PDQ. http://www.cancer.gov/types/lung/hp/non-small-cell-lung-treatment-pdq#link/_361_toc Accessed on February 3, 2016.</ref>
The [[World Health Organization]] ([[World Health Organization|WHO]]) classifies [[tumors]] of the [[lungs]] as follows:<ref name="WHO">{{cite book | last = Travis | first = William | title = Pathology and genetics of tumours of the lung, pleura, thymus, and heart | publisher = IARC Press | location = Lyon | year = 2004 | isbn = 9283224183 }}</ref><ref name="urlwww.jto.org">{{cite web |url=https://www.jto.org/article/S1556-0864(15)33571-1/pdf |title=www.jto.org |format= |work= |accessdate=}}</ref>
**Papillary
**[[Clear cell tumor|Clear cell]]
**[[Small cell]]
**Basaloid
*The table below summarizes the WHO histological classification system for squamous cell carcinoma of the lung.<ref>{{cite book | last = Travis | first = William | title = Pathology and genetics of tumours of the lung, pleura, thymus, and heart | publisher = IARC Press | location = Lyon | year = 2004 | isbn = 9283224183 }}</ref><ref name="pmid16640802">{{cite journal| author=Raz DJ, He B, Rosell R, Jablons DM| title=Bronchioloalveolar carcinoma: a review. | journal=Clin Lung Cancer | year= 2006 | volume= 7 | issue= 5 | pages= 313-22 | pmid=16640802 | doi=10.3816/CLC.2006.n.012 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16640802  }} </ref>


{| style="border: 0px; font-size: 90%; margin: 3px; width: 1000px" align="center"
{| class="wikitable"
! colspan="3" style="padding: 5px 5px; background: #4479BA; font-weight: bold; text-align:center;" |{{fontcolor|#FFF|''WHO histological classification system'' <br><SMALL>Adapted from WHO/IARC (2006) <ref name="radiowiki">  Tumors of the Lung. IARC/WHO https://www.iarc.fr/en/publications/pdfs-online/pat-gen/bb10/bb10-chap1.pdf Accessed on February 22, 2016 </ref></SMALL>}}
| valign="top" |
|+
|+
! colspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" ! | WHO Classification of Lung Tumors
|-
|-
| style="background: #4479BA; width: 300px;" |{{fontcolor|#FFF|''' Main types'''}}
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Histological type
| style="background: #4479BA; width: 300px;" |{{fontcolor|#FFF|''' Subtypes'''}}
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Subtype
| style="background: #4479BA; width: 300px;" |{{fontcolor|#FFF|''' Prevalence'''}}
|-
|-
| style="padding: 0 5px; background: #DCDCDC" | '''Squamous cell carcinoma'''
! colspan="2" style="background: #707070; color: #FFFFFF; text-align: center;" |Epithelial tumors
| style="padding: 5px 5px; background: #F5F5F5;" |
*Papillary       
*Clear cell       
*Small cell
*Basaloid
| style="padding: 5px 5px; background: #F5F5F5;" |
*25% of lung cancers
|-
|-
| style="background: #DCDCDC; padding: 5px; text-align: center;" |'''[[Squamous cell carcinoma of the lung|Squamous cell carcinoma]]'''
|
* Keratinizing squamous cell carcinoma
* Nonkeratinizing squamous cell carcinoma
* Basaloid squamous cell carcinoma
* Preinvasive lesion
** Squamous cell carcinoma in situ
|}
|}



Latest revision as of 18:29, 27 February 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Trusha Tank, M.D.[2]

Overview

Squamous cell carcinoma of the lung may be classified according to the WHO histological classification system into 4 main types: Keratinizing squamous cell carcinoma, nonkeratinizing squamous cell carcinoma, basaloid squamous cell carcinoma and preinvasive lesion.

WHO Histological Classification

The World Health Organization (WHO) classifies tumors of the lungs as follows:[1][2]

WHO Classification of Lung Tumors
Histological type Subtype
Epithelial tumors
Squamous cell carcinoma
  • Keratinizing squamous cell carcinoma
  • Nonkeratinizing squamous cell carcinoma
  • Basaloid squamous cell carcinoma
  • Preinvasive lesion
    • Squamous cell carcinoma in situ

References

  1. Travis, William (2004). Pathology and genetics of tumours of the lung, pleura, thymus, and heart. Lyon: IARC Press. ISBN 9283224183.
  2. "www.jto.org".


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