Splenic marginal zone lymphoma natural history, complications and prognosis: Difference between revisions
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[[Hemoglobin]] level of less than 12 g/dL, [[lactate dehydrogenase]] level higher than normal, blood serum [[albumin]] levels of less than 3.5 g/dL, and some genetic mutations, such as mutations in ''NOTCH2'' are associated with a particularly poor prognosis among patients with splenic marginal zone lymphoma. | [[Hemoglobin]] level of less than 12 g/dL, [[lactate dehydrogenase]] level higher than normal, blood serum [[albumin]] levels of less than 3.5 g/dL, and some genetic mutations, such as mutations in ''NOTCH2'' are associated with a particularly poor prognosis among patients with splenic marginal zone lymphoma. | ||
==Prognosis== | ==Prognosis== | ||
* Poor prognosis criteria <ref name="Arcaini2006">{{cite journal|last=Arcaini|first=L.|year=2006|title=Splenic marginal zone lymphoma: a prognostic model for clinical use|journal=Blood|volume=107|issue=12|pages=4643–4649|issn=0006-4971|doi=10.1182/blood-2005-11-4659}}</ref> | * Poor prognosis criteria for splenic marginal zone lymphoma include: <ref name="Arcaini2006">{{cite journal|last=Arcaini|first=L.|year=2006|title=Splenic marginal zone lymphoma: a prognostic model for clinical use|journal=Blood|volume=107|issue=12|pages=4643–4649|issn=0006-4971|doi=10.1182/blood-2005-11-4659}}</ref> | ||
:* [[Hemoglobin]] level of less than 12 g/dL | :* [[Hemoglobin]] level of less than 12 g/dL | ||
:* [[Lactate dehydrogenase]] level higher than normal | :* [[Lactate dehydrogenase]] level higher than normal | ||
Revision as of 16:50, 14 January 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]
Overview
Hemoglobin level of less than 12 g/dL, lactate dehydrogenase level higher than normal, blood serum albumin levels of less than 3.5 g/dL, and some genetic mutations, such as mutations in NOTCH2 are associated with a particularly poor prognosis among patients with splenic marginal zone lymphoma.
Prognosis
- Poor prognosis criteria for splenic marginal zone lymphoma include: [1]
- Hemoglobin level of less than 12 g/dL
- Lactate dehydrogenase level higher than normal
- Blood serum albumin levels of less than 3.5 g/dL
- Some genetic mutations, such as mutations in NOTCH2, are also correlated with shorter survival
References
- ↑ Arcaini, L. (2006). "Splenic marginal zone lymphoma: a prognostic model for clinical use". Blood. 107 (12): 4643–4649. doi:10.1182/blood-2005-11-4659. ISSN 0006-4971.