Smallpox medical therapy: Difference between revisions

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* Reserved access to the [[virus]]
* Reserved access to the [[virus]]


The main form of treatment is to keep the patient comfortable throughout infection and prevent concomitant infections. This can be achieved by:
The main form of treatment is to keep the patient comfortable throughout [[infection]] and prevent concomitant [[infections]]. This can be achieved by:
* [[IV]] fluids for hydration
* [[IV]] fluids for [[hydration]]
* Antibiotics for concomitant bacterial infections
* [[Antibiotics]] for concomitant [[bacterial infections]]
* Antiviral drugs for concomitant viral infections
* [[Antiviral]] drugs for concomitant [[viral infections]]
* Antipyretics to manage the fever
* [[Antipyretics]] to manage the [[fever]]
* Analgesic drugs to manage the pain
* [[Analgesic drugs]] to manage the [[pain]]


==References==
==References==

Revision as of 02:49, 11 July 2014

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: João André Alves Silva, M.D. [2]

Overview

There is no antiviral treatment for smallpox. In case of disease, it is only possible to manage the wellbeing of the patient, hydrate and administer certain drugs to treat concomitant bacterial and/or viral infections.

Medical Therapy

So far none of the antiviral drugs have been proven effective against the smallpox virus. The investigation for a suitable drug has been impaired by:[1][2]

  • Absence of natural disease
  • Difficulty in finding an animal host
  • Reserved access to the virus

The main form of treatment is to keep the patient comfortable throughout infection and prevent concomitant infections. This can be achieved by:

References

  1. Moore, Zack S; Seward, Jane F; Lane, J Michael (2006). "Smallpox". The Lancet. 367 (9508): 425–435. doi:10.1016/S0140-6736(06)68143-9. ISSN 0140-6736.
  2. Smee DF, Sidwell RW (2003). "A review of compounds exhibiting anti-orthopoxvirus activity in animal models". Antiviral Res. 57 (1–2): 41–52. PMID 12615302.

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