Sleep apnea differential diagnosis: Difference between revisions

Jump to navigation Jump to search
No edit summary
No edit summary
Line 8: Line 8:
==Differential Diagnosis==
==Differential Diagnosis==


*Sleep fragmentation
{| {{table}}
*Fatigue
*Usage of long-acting opioid medication<ref name=DSMV>{{cite book | title = Diagnostic and statistical manual of mental disorders : DSM-5 | publisher = American Psychiatric Association | location = Washington, D.C | year = 2013 | isbn = 0890425558 }}</ref>
Asthma
Chronic Obstructive Pulmonary Disease
Depression
Gastroesophageal Reflux Disease
Hypothyroidism
Narcolepsy
Periodic Limb Movement Disorder


Pseudocentral sleep apnea: Patients with diaphragmatic paralysis and other neuromuscular diseases, who are dependent on accessory muscles of breathing to maintain ventilation, may appear to have central apneas during rapid eye movement (REM) sleep. This is due to the REM atonia of skeletal muscles. Many of these patients actually have obstructive sleep apnea but do not have enough diaphragmatic excursions to be recorded by the piezoelectric belts used during routine PSG. A history of neuromuscular disease and worsening of central apneas during REM sleep should alert to the possibility of pseudocentral apnea.
| align="center" style="background:#f0f0f0;"|'''Disease/Condition'''


Sleep-related hypoventilation syndrome: Sleep-related hypoventilation with central sleep apneas can be observed in many conditions, such as neuromuscular weakness or chronic obstructive pulmonary disease. These conditions are characterized by a history of a preexisting disorder of hypoventilation, elevated resting PaCO2, and severe oxygen desaturation during sleep, which is more prominent during REM sleep in contrast to primary centralSLEEP APNEA and Cheyne-Stokes breathing-central sleep apnea (CSB-CSA), which are mostly observed during NREM sleep.
| align="center" style="background:#f0f0f0;"|'''Differentiating Signs/Symptoms'''


| align="center" style="background:#f0f0f0;"|'''Differentiating Tests'''
|-
| Cheyne-Stokes respiration (CSB)||Recurrent episodes of apnea with absence of respiratory effort; CSB is associated with cerebrovascular disease, CHF, or renal failure ||In CSB, a crescendo-decrescendo change in breathing amplitude interpersed by episodes of central sleep apnea or hypoapnea would be seen
|-
| Narcolepsy||Level of sleepiness in narcolepsy may be higher in Epworth Sleepiness Scale; may have cataplexy, hypnagogic hallucincations, and sleep paralysis||A polysomnography should be performed to rule out OSA; a multiple sleep latency test (MLST) can assess for naroclepsy
|-
| Insufficient sleep||Difficult to differentiate clinically||A polysomnography should be performed to rule out OSA; a sleep diary should used
|-
| Inadequate sleep hygiene||Irregular sleep schedule with frequent napping; frequent use of alcohol, nicotine, and caffeine; poor bedroom environment||A polysomnography should be performed to rule out OSA; diagnosis is usually clinical
|-
| Periodic limb movement disorder||Patients describe an urge to move legs due to discomfort during periods of inactivity (including sleep); patients have excessive sleepiness||A polysomnography should demonstrate limb movements and rule out OSA
|-
| Nocturnal gastroesphageal reflux||Results in nocturnal restlessness, choking episodes during sleep, frequent awakening, and labored breathing||A polysomnography should be performed to rule out OSA
|-
| Nocturnal asthma||Can present with nocturnal choking, gasping, coughing, or shortness of breath||A polysomnography should be performed to rule out OSA; PULMONARY                                function tests can be performed
|-
| Primary snoring||More common than OSA||A polysomnography should be performed to rule out OSA
|-
| Nocturnal panic attacks||Can present with nocturnal choking, gasping, coughing, or shortness of breath||A polysomnography should be performed to rule out OSA; a psychiatric history should be performed
|-
| Congestive heart failure||Can present with nocturnal choking, gasping, coughing, or shortness of breath||A polysomnography should be performed to rule out OSA; EKG, chest x-ray, blood tests, stress testing, and cardiac catheterization can be performed
|-
| Sleep-related laryngospasm||Can present with nocturnal choking, gasping, coughing, or shortness of breath||A polysomnography should be performed to rule out OSA
|-
| Chronic fatigue syndrome||Daytme fatigue is the only complaint||A polysomnography should be performed to rule out OSA
|-
| Depression||Can present with fatigue and feelings of hopelessness||A polysomnography should be performed to rule out OSA; a psychiatric history should be performed
|-
| Pseudocentral sleep apnea||These patients with diaphragmatic paralysis depend on accessory muscles during breathing and may have apnea during REM sleep (sleep apnea is mostly observed during non-REM sleep); history of neuromuscular disease||A polysomnography should be performed to rule out OSA; various neuromuscular disease tests can be performed
|}


==References==
==References==

Revision as of 14:09, 6 July 2015

Sleep Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Sleep apnea from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Criteria

History and Symptoms

Physical Examination

Laboratory Findings

Polysomnography

Home Oximetry

CT

MRI

Ultrasound

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Sleep apnea differential diagnosis On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Sleep apnea differential diagnosis

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Sleep apnea differential diagnosis

CDC on Sleep apnea differential diagnosis

Sleep apnea differential diagnosis in the news

Blogs on Sleep apnea differential diagnosis

Directions to Hospitals Treating Sleep apnea

Risk calculators and risk factors for Sleep apnea differential diagnosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Jesus Rosario Hernandez, M.D. [2]

Overview

Sleep must be differentiated from other diseases that cause loud snoring, fatigue, or daytime sleepiness.

Differential Diagnosis

Disease/Condition Differentiating Signs/Symptoms Differentiating Tests
Cheyne-Stokes respiration (CSB) Recurrent episodes of apnea with absence of respiratory effort; CSB is associated with cerebrovascular disease, CHF, or renal failure In CSB, a crescendo-decrescendo change in breathing amplitude interpersed by episodes of central sleep apnea or hypoapnea would be seen
Narcolepsy Level of sleepiness in narcolepsy may be higher in Epworth Sleepiness Scale; may have cataplexy, hypnagogic hallucincations, and sleep paralysis A polysomnography should be performed to rule out OSA; a multiple sleep latency test (MLST) can assess for naroclepsy
Insufficient sleep Difficult to differentiate clinically A polysomnography should be performed to rule out OSA; a sleep diary should used
Inadequate sleep hygiene Irregular sleep schedule with frequent napping; frequent use of alcohol, nicotine, and caffeine; poor bedroom environment A polysomnography should be performed to rule out OSA; diagnosis is usually clinical
Periodic limb movement disorder Patients describe an urge to move legs due to discomfort during periods of inactivity (including sleep); patients have excessive sleepiness A polysomnography should demonstrate limb movements and rule out OSA
Nocturnal gastroesphageal reflux Results in nocturnal restlessness, choking episodes during sleep, frequent awakening, and labored breathing A polysomnography should be performed to rule out OSA
Nocturnal asthma Can present with nocturnal choking, gasping, coughing, or shortness of breath A polysomnography should be performed to rule out OSA; PULMONARY function tests can be performed
Primary snoring More common than OSA A polysomnography should be performed to rule out OSA
Nocturnal panic attacks Can present with nocturnal choking, gasping, coughing, or shortness of breath A polysomnography should be performed to rule out OSA; a psychiatric history should be performed
Congestive heart failure Can present with nocturnal choking, gasping, coughing, or shortness of breath A polysomnography should be performed to rule out OSA; EKG, chest x-ray, blood tests, stress testing, and cardiac catheterization can be performed
Sleep-related laryngospasm Can present with nocturnal choking, gasping, coughing, or shortness of breath A polysomnography should be performed to rule out OSA
Chronic fatigue syndrome Daytme fatigue is the only complaint A polysomnography should be performed to rule out OSA
Depression Can present with fatigue and feelings of hopelessness A polysomnography should be performed to rule out OSA; a psychiatric history should be performed
Pseudocentral sleep apnea These patients with diaphragmatic paralysis depend on accessory muscles during breathing and may have apnea during REM sleep (sleep apnea is mostly observed during non-REM sleep); history of neuromuscular disease A polysomnography should be performed to rule out OSA; various neuromuscular disease tests can be performed

References

Template:WH Template:WS