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*During history taking ask for prior upper respiratory infections, use of tobacco, anatomic anomalies, acid reflux disease, and immunologic state.
*During history taking ask for prior upper respiratory infections, use of tobacco, anatomic anomalies, acid reflux disease, and immunologic state.
*Look after major and minor signs of sinusitis:
*Look after major and minor signs of sinusitis:
*Major: purulent rhinorrhea, nasal obstruction, facial pain, hyposmia, anosmia, fever
**Major: purulent rhinorrhea, nasal obstruction, facial pain, hyposmia, anosmia, and fever
*Minor:
**Minor: headache, cough, halitosis, fatigue, otalgia, and dental pain
*During physical examination look for purulent nasal discharge, rhinolalia, edema, periorbitary erythema, and pain to palpation and percussion to the frontomaxilary region


==Don'ts==
==Don'ts==


* Avoid inappropriate use of antibiotics in acute presentations since the vast majority of these infections are viral.
*Avoid inappropriate use of antibiotics in acute presentations since the vast majority of these infections are viral.
* Avoid ordering imaging studies in cases where the diagnosis is well established clinically.
*Avoid ordering imaging studies in cases where the diagnosis is well established clinically.


==References==
==References==

Revision as of 17:02, 25 August 2020


Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Moises Romo M.D.

Overview

Rhinosinusitis is the inflammation of the nasal mucosa and paranasal sinuses. The terms sinusitis and rhinosinusitis are used interchangeably, although rhinosinusitis is preferred because inflammation of the paranasal sinuses rarely ever occurs without concurrent inflammation of the nasal mucosa. The cause of rhinosinusitis is mostly infectious, although it can be associated with other medical conditions such as allergies. The diagnosis is primarily clinical and imaging and other diagnostic studies are not necessary for diagnosis.

Causes

Life Threatening Causes

  • Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated.
  • There are no known causes of life-threatening causes of sinusitis.

Common Causes

Infectious causes of rhinosinusitis include viruses, bacteria, and fungi:[1][2]

Diagnosis and Treatment

Shown below is an algorithm summarizing the diagnosis and treatment of sinusitis according to the American Academy of Otolaryngology, Head, and Neck Surgery guidelines:[3]

 
 
 
 
 
 
 
 
 
 
Adult with possible sinusitis
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Duration ≤ 4w
 
 
 
Duration 4-12w
 
 
 
Duration ≥ 12w
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
No
 
Meets criteria for acute rhinosinusitis?
 
 
 
“Subacute” sinusitis excluded from guideline
 
 
 
Signs and symptoms of chronic rhinosinusitis?
 
No
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Viral upper respiratory infection
 
Yes
 
 
 
 
 
 
 
 
 
Yes
 
Not chronic rhinosinusitis
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
No
 
Meets criteria for acute bacterial rhinosinusitis?
 
Yes
 
Acute bacterial rhinosinusitis
 
Documented sinonasal inflammation?
 
No
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Viral acute rhinosinusitis
 
 
 
 
 
Yes
 
Complication suspected?
 
Yes
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Obtain radiologic imaging
 
No
 
Chronic rhinosinusitis
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Do not obtain radiologic imaging
 
Confirm the presence or absence of nasal polyps
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
No
 
Absense of complications?
 
Recommend symptomatic relief for acute bacterial rhinosinusitis
 
Recommend saline nasal irrigation and/or topical intranasal corticosteroids
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Manage complication and acute bacterial rhinosinusitis
 
 
 
 
 
Offer watchful waiting OR prescribe antibiotic based on shared decision-making
 
Recommend saline nasal irrigation and/or topical intranasal corticosteroids
 
Do not prescribe topical or systemic antifungal therapy
 
Assess patient for chronic conditions that would modify management
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Decision to proceed with watchful waiting
 
 
 
 
 
Decision to proceed with initial antibiotic therapy
 
 
 
 
 
Option of testing for allergy and immune function
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Offer a safety-net or wait-and-see antibiotic prescription
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Medical or surgical management as appropriate
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Treatment failure
 
Yes
 
Prescribe amoxicillin, with or without clavulanate
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
No
 
 
 
 
 
Treatment failure?
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Recurrent acute bacterial rhinosinusitis?
 
 
No
 
 
 
Yes
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
No
 
 
 
 
 
 
 
 
Exclude complications and other causes of illness; if diagnosis of acute bacterial rhinosinusitis is confirmed prescribe an alternate antibiotic
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Management complete


Do's

  • During history taking ask for the exposure to toxins, toxic waste, wood, immersion in contaminated water, solvents, gas or oil refineries, leather tanning, textiles, drug addictions, and chronic administration of intranasal drugs.
  • During history taking ask for prior upper respiratory infections, use of tobacco, anatomic anomalies, acid reflux disease, and immunologic state.
  • Look after major and minor signs of sinusitis:
    • Major: purulent rhinorrhea, nasal obstruction, facial pain, hyposmia, anosmia, and fever
    • Minor: headache, cough, halitosis, fatigue, otalgia, and dental pain
  • During physical examination look for purulent nasal discharge, rhinolalia, edema, periorbitary erythema, and pain to palpation and percussion to the frontomaxilary region

Don'ts

  • Avoid inappropriate use of antibiotics in acute presentations since the vast majority of these infections are viral.
  • Avoid ordering imaging studies in cases where the diagnosis is well established clinically.

References

  1. Brook I (2011). "Microbiology of sinusitis". Proc Am Thorac Soc. 8 (1): 90–100. doi:10.1513/pats.201006-038RN. PMID 21364226.
  2. deShazo RD, Chapin K, Swain RE (1997). "Fungal sinusitis". N. Engl. J. Med. 337 (4): 254–9. doi:10.1056/NEJM199707243370407. PMID 9227932.
  3. Rosenfeld, Richard M.; Piccirillo, Jay F.; Chandrasekhar, Sujana S.; Brook, Itzhak; Ashok Kumar, Kaparaboyna; Kramper, Maggie; Orlandi, Richard R.; Palmer, James N.; Patel, Zara M.; Peters, Anju; Walsh, Sandra A.; Corrigan, Maureen D. (2015). "Clinical Practice Guideline (Update): Adult Sinusitis". Otolaryngology–Head and Neck Surgery. 152 (2_suppl): S1–S39. doi:10.1177/0194599815572097. ISSN 0194-5998.


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