Sigma-2 receptor
The sigma-2 receptor is a sigma receptor which preferentially binds to siramesine[1] and PB28.[2]
Unlike sigma-1 receptor, it has not yet been cloned.
Activation of the receptor can cause apoptosis.[3]
External links
- sigma-2+receptor at the US National Library of Medicine Medical Subject Headings (MeSH)
References
- ↑ Skuza G, Rogóz Z (2006). "The synergistic effect of selective sigma receptor agonists and uncompetitive NMDA receptor antagonists in the forced swim test in rats". J. Physiol. Pharmacol. 57 (2): 217–29. PMID 16845227.
- ↑ Cassano G, Gasparre G, Contino M; et al. (2006). "The sigma-2 receptor agonist PB28 inhibits calcium release from the endoplasmic reticulum of SK-N-SH neuroblastoma cells". Cell Calcium. 40 (1): 23–8. doi:10.1016/j.ceca.2006.03.004. PMID 16687172.
- ↑ "Wayne D. Bowen - MPPB Faculty :: Brown University". Retrieved 2008-01-07.