Sick sinus syndrome natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Natural History, Complications and Prognosis

Natural History

Brief, but gradually worsening cardiac rhythm abnormalities typically ensue as part of the natural history of SSS. These disorders have been associated with higher rates of cardiovascular events and increased mortality rates. With time, the rhythm disturbances tend to evolve, along with higher rates of thromboembolic events. ^[1]

Complications

Angina
Decreased exercised capacity
Fainting (syncope)
Falls or injury caused by fainting
Heart failure
Poor heart pumping

Prognosis

The syndrome is progressive, which means it usually gets worse over time.

The long-term outlook is excellent for people who have a permanent pacemaker implanted.

The long-term progression of SSS is mostly related to the presence and severity of associated coronary or hypertensive cardiac disease. ^[2]

References

↑ Lien WP, Lee YS, Chang FZ, Lee SY, Chen CM, Tsai HC (1977). "The sick sinus syndrome: natural history of dysfunction of the sinoatrial node". Chest. 72 (5): 628–34. PMID 913143.
↑ Rodriguez RD, Schocken DD (1990). "Update on sick sinus syndrome, a cardiac disorder of aging". Geriatrics. 45 (1): 26–30, 33–6. PMID 2403955.

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[pmid913143-1] Lien WP, Lee YS, Chang FZ, Lee SY, Chen CM, Tsai HC (1977). "The sick sinus syndrome: natural history of dysfunction of the sinoatrial node". Chest. 72 (5): 628–34. PMID 913143.

[pmid2403955-2] Rodriguez RD, Schocken DD (1990). "Update on sick sinus syndrome, a cardiac disorder of aging". Geriatrics. 45 (1): 26–30, 33–6. PMID 2403955.

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