Serratia infection differential diagnosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Urinary Tract Infection

Serratia urinary tract infection (UTI) must be differentiated from other causes of abdominal discomfort, dysuria, hematuria, pyuria, and/or polyuria, such as:

• Other causes of UTI

• E. coli
• Enterobacter spp.
• Enterococcus spp.
• Haemophilus spp.
• Klebsiella spp.
• Mycoplasma spp.
• Proteus spp.
• Providencia spp.
• Pseudomonas spp.
• Staphylococcus spp.
• Ureaplasma spp.
• Tuberculous infection of the urinary tract
• Sexually transmitted infections (e.g. Gonorrhea or Chlamydia)
• Parasiticc infections (e.g. threadworms)
• Viruses (e.g. HSV)

• Pyelonephritis (acute or chronic)
• Appendicitis
• Benign prostatic hypertrophy
• Prostatitis
• Chronic pelvic pain
• Urinary tract obstruction
• Vesicoureteral reflux
• Polycystic kidney disease
• Metal toxicity
• Sarcoidosis
• Genitourinary malignancy (e.g. bladder cancer)
• Renal transplant rejection
• Periurethral disease
• Interstitial cystitis
• Atrophic vaginitis
• Vulvovaginitis
• Urethritis
• Behcet disease
• Epididymitis
• Pregnancy
• Colovesical fistula
• Diverticulitis
• Glomerulonephritis
• Nephrolithiasis
• Trauma
• Ureterocele

Pneumonia

Serratia pneumonia must be differentiated from other causes of fever, chest pain, productive cough, dyspnea, and blood per sputum, such as:

• Other infectious causes of pneumonia:

• Streptococcus spp.
• Staphylococcus spp.
• Anaerobes
• Chlamydia spp.
• E. coli
• Haemophilus spp.
• Legionella spp.
• Tuberculosis or non-tuberculous Mycobacterium spp. (e.g. MAC)
• Mycoplasma spp.
• Moraxella spp.
• Pseudomonas spp.
• Fungal infections (e.g. Candida, Aspergillus)
• Pneumocystis pneumoniae infection
• Viral pneumonia (e.g. influenza, parainfluenza, VZV, HSV, RSV, CMV, adenovirus, metapneumovirus, coronavirus, measles)
• Atypical infections (Q-fever, tularemia, psittacosis)

• Bronchiolitis
• Epiglottitis
• Asthma
• Respiratory distress syndrome
• Atelectasis
• Broncchiectasis
• Bronchitis
• COPD exacerbation
• Foreign body aspiration
• Lung abscess
• Respiratory failure
• Pulmonary embolism
• Chemical pneumonitis
• Sepsis
• Sarcoidosis
• Heart failure
• Pulmonary of thoracic malignancy

Intra-abdominal Infection

Serratia intra-abdominal infection must be differentiated from other causes of abdominal pain and fever, such as:

• Other intra-abdominal infections

• E. coli
• Streptococcus spp.
• Lactobacillus spp.
• Enterococci
• Yersinia spp.
• Klebsiella spp.
• Campylobacter spp.
• Acinetobacter spp.
• Clostridium spp.
• Proteus spp.
• Pseudomonas spp.
• Anaerobes
• Fungal infections (e.g. Candida, histoplasmosis, cryptococcosis, coccidiomycosis)
• Parasitic infections (e.g. Amoebiasis, giardiasis, Cryptosporidium)

• Peritonitis
• Familial Mediterranean fever
• Inflammatory bowel disease
• Celiac disease
• Meckel's diverticulum
• Myocardial infarction
• Abdominal tumors
• Hepatitis and liver disease
• Perforated viscus
• Peritoneal cysts
• Pyelonephritis
• Splenosis
• Vasculitis (E.g. Henoch-Schonlein purpura, systemic lupus erythematosus, polyarteritis nodosa)
• Appendicitis
• Ischemic colitis
• Portal or mesenteric vein thrombosis
• Abdominal abscess
• Abdominal obstrucction
• Volvolus
• Intussusception
• Ileus
• Pancreatitis, pancreatic pseudocyst, pancreatic abscess or pancreatic cancer
• Cholecystitis or cholangitis
• Diverticulitis
• Pelvic inflammatory disease
• Pregnancy
• Endometritis
• Sarcoidosis

Meningitis / Cerebral Abscess

Serratia meningitis / cerebral abscess must be differentiated from other causes of headache, fever, and altered mental status, such as:

Endocarditis

Serratia endocarditis must be differentiated from other causes of fever, petechiae, and abnormal heart murmurs, such as:

HEENT Infections

Serratia HEENT infections must be differentiated from other causes of eye infections (e.g. keratitis, endophthalmitis, and conjunctivitis), parotitis, or otitis, such as:

Soft Tissue Infections

Serratia soft tissue infections must be differentiated from other causes of osteomyelitis, cellulitis, and phlebitis, such as: