Schistosomiasis epidemiology and demographics: Difference between revisions

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{{Schistosomiasis}}
{{Schistosomiasis}}
{{CMG}}
{{CMG}} ; {{AE}} {{ADG}}


==Overview==
==Overview==
==Epidemiology and Demographics==
The prevalence of schistosomiasis is approximately 268 per 100,000 individuals worldwide. More than 600 million persons are exposed to Schistosoma parasites, 200 million persons are infected, and 20 million symptomatic cases of schistosomiasis are reported worldwide. All age groups are vulnerable to Schistosoma infection, but school-aged children and adolescents living in endemic areas tend to have the highest intensity of disease. There is no racial predilection to schistosomiasis. Schistosomiasis affects men and women equally.
The disease is found in tropical countries in Africa, Caribbean, eastern South America, east Asia and in the Middle East. ''[[Schistosoma mansoni]]'' is found in parts of South America and the Caribbean, Africa, and the Middle East; ''S. haematobium'' in Africa and the Middle East; and ''S. japonicum'' in the Far East.  ''S. mekongi'' and ''S. intercalatum'' are found focally in Southeast Asia and central West Africa, respectively.


An estimated 207 million people have the disease, 120 million symptomatic.  A few countries have eradicated the disease, and many more are working towards it. The [[World Health Organization]] is promoting efforts working towards this goal. In some cases, urbanization, pollution, and/or consequent destruction of snail habitat has reduced exposure, with a subsequent decrease in new infections. The most common way of getting schistosomiasis in developing countries is by wading or swimming in lakes, ponds and other bodies of water which are infested with the snails (usually of the ''[[Biomphalaria]]'', ''[[Bulinus]]'', or ''Oncomelania'' genus) that are the [[natural reservoir]]s of the ''Schistosoma'' pathogen.
==Epidemiology==
===Incidence and prevalence===
*The prevalence of schistosomiasis is approximately 268 per 100,000 individuals worldwide.


[[Image:Schistosomiasis world map - DALY - WHO2002.svg|thumb|center|[[Disability-adjusted life year]] for schistosomiasis per 100,000&nbsp;inhabitants.<div class="references-small" style="-moz-column-count:3; column-count:3;">
==Demographics==
{{legend|#b3b3b3|no data}}
===Age===
{{legend|#ffff65|less than 50}}
*Patients of all age groups may develop schistosomiasis, but school-aged children and [[Adolescent|adolescents]] living in [[endemic]] areas tend to have the highest [[intensity]] of [[disease]].<ref name="pmid26224883">{{cite journal |vauthors=Weerakoon KG, Gobert GN, Cai P, McManus DP |title=Advances in the Diagnosis of Human Schistosomiasis |journal=Clin. Microbiol. Rev. |volume=28 |issue=4 |pages=939–67 |year=2015 |pmid=26224883 |pmc=4548261 |doi=10.1128/CMR.00137-14 |url=}}</ref>
{{legend|#fff200|50-75}}
{{legend|#ffdc00|75-100}}
{{legend|#ffc600|100-150}}
{{legend|#ffb000|150-200}}
{{legend|#ff9a00|200-250}}
{{legend|#ff8400|250-300}}
{{legend|#ff6e00|300-350}}
{{legend|#ff5800|350-400}}
{{legend|#ff4200|400-450}}
{{legend|#ff2c00|450-500}}
{{legend|#cb0000|more than 500}}
</div>]]
The disease is found in [[Tropics|tropical]] countries in [[Africa]], the [[Caribbean]], eastern [[South America]], [[Southeast Asia]] and in the [[Middle East]]. ''[[Schistosoma mansoni]]'' is found in parts of South America and the Caribbean, Africa, and the Middle East; ''S. haematobium'' in Africa and the Middle East; and ''S. japonicum'' in the [[Far East]]. ''S. mekongi'' and ''S. intercalatum'' are found locally in [[Southeast Asia]] and central [[West Africa]], respectively.


Among human parasitic diseases, schistosomiasis (sometimes called bilharziasis) ranks second behind [[malaria]] in terms of socio-economic and public health importance in tropical and subtropical areas. The disease is endemic in 74-76 developing countries,{{Verify source|November 2009|date=November 2009}} infecting more than 207&nbsp;million people, 85% of whom live in Africa. They live in rural agricultural and peri-urban areas, and placing more than 700&nbsp;million people at risk.<ref>{{cite journal
===Race===
| author = Oliveira, G.
*There is no [[racial]] predilection to schistosomiasis.
| coauthors = Rodrigues N.B., Romanha, A.J., Bahia, D.
| year = 2004
| title = Genome and Genomics of Schistosomes
| journal = Canadian Journal of Zoology
| volume = 82
| issue = 2
| pages = 375–90
| doi = 10.1139/Z03-220
| url = http://www.ingentaconnect.com/content/nrc/cjz/2004/00000082/00000002/art00012
}}</ref>


Of the infected patients, 20&nbsp;million suffer severe consequences from the disease.<ref>{{cite journal |author=Kheir MM, Eltoum IA, Saad AM, Ali MM, Baraka OZ, Homeida MM |title=Mortality due to schistosomiasis mansoni: a field study in Sudan |journal=Am. J. Trop. Med. Hyg. |volume=60 |issue=2 |pages=307–10 |year=1999 |month=February |pmid=10072156 }}</ref> Some estimate that there are approximately 20,000 deaths related to schistosomiasis yearly.{{Citation needed|date=November 2009}} In many areas, schistosomiasis infects a large proportion of children under 14 years of age. An estimated 600&nbsp;million people worldwide are at risk from the disease.
===Gender===
*Schistosomiasis affects men and women equally.


A few countries have eradicated the disease, and many more are working toward it.{{Citation needed|date=November 2009}} The [[World Health Organization]] is promoting these efforts. In some cases, urbanization, pollution, and/or consequent destruction of snail habitat has reduced exposure, with a subsequent decrease in new infections. The most common way of getting schistosomiasis in developing countries is by wading or swimming in lakes, ponds and other bodies of water that are infested with the [[snail]]s (usually of the genera ''[[Biomphalaria]]'', ''[[Bulinus]]'', or ''[[Oncomelania]]'') that are the [[natural reservoir]]s of the ''Schistosoma'' pathogen.
===Geographic Disrtubution===
*The [[disease]] is found in [[Tropics|tropical]] countries in [[Africa]], [[Caribbean]], Eastern [[South America]], [[Southeast Asia]] and in [[Middle East]].
* ''[[Schistosoma mansoni]]'' is found in parts of South America and Caribbean, Africa, and Middle East.
* ''[[Schistosoma haematobium|S. haematobium]]'' is found in Africa and Middle East; and ''[[Schistosoma japonicum|S. japonicum]]'' in [[Far East]].
*''[[Schistosoma mekongi|S. mekongi]]'' and ''[[Schistosoma intercalatum|S. intercalatum]]'' are found locally in [[Southeast Asia]] and Central [[West Africa]], respectively.
*Schistosomiasis is [[endemic]] in 74-76 developing countries,{{Verify source|November 2009|date=November 2009}} infecting more than 207&nbsp;million people, 85% of whom live in Africa.<ref name="OliveiraRodrigues2004">{{cite journal|last1=Oliveira|first1=Guilherme|last2=Rodrigues|first2=Nilton B|last3=Romanha|first3=Alvaro J|last4=Bahia|first4=Diana|title=Genome and genomics of schistosomes|journal=Canadian Journal of Zoology|volume=82|issue=2|year=2004|pages=375–390|issn=0008-4301|doi=10.1139/z03-220}}</ref>
 
{| class="wikitable"
!Organ involved
!Species
!Geographical distribution
|-
| rowspan="4" |[[Intestinal]] [[schistosomiasis]]
|''[[Schistosoma mansoni]]''
|Africa, Middle East, Caribbean, Brazil, Venezuela and Suriname
|-
|''[[Schistosoma japonicum]]''
|China, Indonesia, Philippines
|-
|''[[Schistosoma mekongi]]''
|Several districts of Cambodia and the Lao People’s Democratic Republic
|-
|''Schistosoma guineensis''
''[[Schistosoma intercalatum]]''
|Rain forest areas of Central Africa
|-
|[[Urogenital]] [[schistosomiasis]]
|''[[Schistosoma haematobium]]''
|Africa, Middle East, Corsica (France)
|}


==References==
==References==
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{{Reflist|2}}
{{Reflist|2}}


[[Category:Disease]]
[[Category:Water-borne diseases]]
[[Category:Water-borne diseases]]
[[Category:Parasitic diseases]]
[[Category:Parasitic diseases]]
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[[Category:Hepatology]]
[[Category:Hepatology]]
[[Category:Neglected diseases]]
[[Category:Neglected diseases]]
[[Category:Infectious disease]]

Latest revision as of 18:43, 18 September 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]

Overview

The prevalence of schistosomiasis is approximately 268 per 100,000 individuals worldwide. More than 600 million persons are exposed to Schistosoma parasites, 200 million persons are infected, and 20 million symptomatic cases of schistosomiasis are reported worldwide. All age groups are vulnerable to Schistosoma infection, but school-aged children and adolescents living in endemic areas tend to have the highest intensity of disease. There is no racial predilection to schistosomiasis. Schistosomiasis affects men and women equally.

Epidemiology

Incidence and prevalence

  • The prevalence of schistosomiasis is approximately 268 per 100,000 individuals worldwide.

Demographics

Age

Race

  • There is no racial predilection to schistosomiasis.

Gender

  • Schistosomiasis affects men and women equally.

Geographic Disrtubution

Organ involved Species Geographical distribution
Intestinal schistosomiasis Schistosoma mansoni Africa, Middle East, Caribbean, Brazil, Venezuela and Suriname
Schistosoma japonicum China, Indonesia, Philippines
Schistosoma mekongi Several districts of Cambodia and the Lao People’s Democratic Republic
Schistosoma guineensis

Schistosoma intercalatum

Rain forest areas of Central Africa
Urogenital schistosomiasis Schistosoma haematobium Africa, Middle East, Corsica (France)

References

  1. Weerakoon KG, Gobert GN, Cai P, McManus DP (2015). "Advances in the Diagnosis of Human Schistosomiasis". Clin. Microbiol. Rev. 28 (4): 939–67. doi:10.1128/CMR.00137-14. PMC 4548261. PMID 26224883.
  2. Oliveira, Guilherme; Rodrigues, Nilton B; Romanha, Alvaro J; Bahia, Diana (2004). "Genome and genomics of schistosomes". Canadian Journal of Zoology. 82 (2): 375–390. doi:10.1139/z03-220. ISSN 0008-4301.