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| {| border="3"
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| |+
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| ! style="background: #4479BA; width: 150px;" | {{fontcolor|#FFF| Lipomatous tumor}}
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| ! style="background: #4479BA; width: 150px;" | {{fontcolor|#FFF| Age of onset}}
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| ! style="background: #4479BA; width: 150px;" | {{fontcolor|#FFF| Gender preponderance}}
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| ! style="background: #4479BA; width: 150px;" | {{fontcolor|#FFF| Location}}
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| ! style="background: #4479BA; width: 150px;" | {{fontcolor|#FFF| Clinical features}}
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| ! style="background: #4479BA; width: 150px;" | {{fontcolor|#FFF| Pathologic appearance}}
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| ! style="background: #4479BA; width: 150px;" | {{fontcolor|#FFF| Other features}}
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| ! style="background: #4479BA; width: 150px;" | {{fontcolor|#FFF| Pathologic view}}
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| |-
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| ! style="padding: 5px 5px; background: #DCDCDC; " align="left" |Angiolipoma
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| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
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| * Second and third decades of life
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| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
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| * Female < male
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| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
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| * More commonly seen in forearm
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| * May also affect trunk and upper arm
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| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
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| * Subcutaneous nodule
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| * Tender to palpation
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| * Less than 2 cm
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|
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
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| * Encapsulated, yellow nodules with a reddish tinge
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| * A combination of fatty tissue and vascular channels
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| * Fibrin thrombi is present in vascular channels (characteristic finding)
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|
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
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| * Benign
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |[[File:Capture1.PNG|thumb|none|200px|Contributed by Dr. Dharam Ramnani in Webpathology]]
| |
| |-
| |
| ! style="padding: 5px 5px; background: #DCDCDC; " align="left" |Myolipoma
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
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| * Fifth and sixth decades of life
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|
| |
| *
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
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| * Female > male
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| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
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| * More commonly seen in retroperitoneum, abdomen, pelvis, inguinal region, or abdominal wall
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| * May also affect extremities
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| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
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| * Subcutaneous mass which may also engage superficial muscular fascia
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| * Size differs depending on the location
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| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
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| * Partially encapsulated mass with partially yellow-white cut surface
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| * A combination of mature adipocytes and sheets of well-differentiated smooth muscle
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| * No nuclear atypia
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| *Sieve-like appearance at low magnification (due to interspersed location of smooth muscle component)
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|
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| *
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| *
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
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| * Benign
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| * It is usually large and located in the deep soft tissues
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| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |[[File:Capture.PNG|thumb|none|200px|Contributed by Dr. Dharam Ramnani in Webpathology]]
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| |-
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| ! style="padding: 5px 5px; background: #DCDCDC; " align="left" |Myelolipoma
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
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| * Fifth decade of life
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|
| |
| *
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
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| * Female = male
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| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
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| * More commonly seen in adrenal glands
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| * Other possible locations include:
| |
| * thoracic, retroperitoneum and presacral region, mediastinum, liver, and bone
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
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| * Usually asymptomatic
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| * May cause abdominal pain, nausea, and constipation (depending on the location and size)
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| * Uncommonly, may cause retro-peritoneal hemorrhage
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| * 3 to 7 cm
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|
| |
| *
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
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| * A combination of bone marrow elements and adipose tissue in varying proportions
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| * May show myxoid changes
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|
| |
| *
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
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| * Well-circumscribed radiolucent mass in radiologic imaging
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| * May have hromonal activity
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |[[File:Adrenal Myelolipoma MP CTR.jpg|thumb|none|200px|Contributed by Sarahkayb in Wikimedia commons]]
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| |-
| |
| ! style="padding: 5px 5px; background: #DCDCDC; " align="left" |Spindle Cell/Pleomorphic Lipoma
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|
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * Fifth to seventh decades of life
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|
| |
| *
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
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| * Female < male
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| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * More commonly seen in posterior neck, shoulder, and back
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| * It is also reported in oral cavity
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| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
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| * Subcutaneous nodule with firm consistency
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| * Slowly growing and painless
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| * Mostly between 3 to 5 cm
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|
| |
| *
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
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| * Similar to ordinary lipoma
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| * A combination of mature fat cells and spindle cell or pleomorphic elements
| |
| * Lipomatous component may vary in amount
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|
| |
| *
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * Immunohistochemically positive for CD34
| |
| * Benign
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |[[File:Spindle cell lipoma -- intermed mag.jpg|thumb|none|200px|Contributed by Nephron in Wikimedia commons]]
| |
| |-
| |
| !style="padding: 5px 5px; background: #DCDCDC; " align="left" |Chondroid Lipoma
| |
|
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * Third or fourth decade of life
| |
|
| |
| *
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * Female > male
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * More commonly seen in limbs and limb girdles
| |
| * May also involve trunk, and the head and neck region, particularly the oral cavity
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * Slowly growing painless mass
| |
| * Sizes ranges from 1 to 11 cm
| |
|
| |
| *
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * Encapsulated tumor with a yellow, white, or pink-tan cut surface
| |
| * A combination of mature adipocytes in association with nests of vacuolated cells in a myxochondroid or hyalinized fibrous background
| |
|
| |
| *
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * Heterogeneous soft tissue mass in radiologic imaging
| |
| * Benign
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |[[File:Capture2.PNG|thumb|none|200px|Contributed by Dr. Dharam Ramnani in Webpathology]]
| |
| |-
| |
| !style="padding: 5px 5px; background: #DCDCDC; " align="left" |Hibernoma
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * Third decade of life
| |
|
| |
| *
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * Female = male
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * Most commonly seen in thigh
| |
| * May also affect shoulder, back, neck, chest, arm, and abdominal cavity/retroperitoneum
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * Slowly growing, painless, subcutaneous mass
| |
| * Affects intramuscular in 10% of the cases
| |
| *Size varies between 5 to 15 cm
| |
|
| |
| *
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * Well-defined, soft, and mobile mass
| |
| * A combination of vacuolated granular eosinophilic cells with abundant mithochondria and high vascular content
| |
|
| |
| *
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * Immunohistochemically positive for S-100
| |
| * Benign
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |[[File:Hibernoma2.jpg|thumb|none|200px|Contributed by Nephron in Wikimedia commons]]
| |
| |-
| |
| ! style="padding: 5px 5px; background: #DCDCDC; " align="left"|Intramuscular and Intermuscular Lipomas
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * Fourth to seventh decades of life
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * Female < male
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * Most commonly seen in large muscles of the extremities, especially in thigh, shoulder, and upper arm
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * Painless, slowly growing mass
| |
| * Visible during muscle contraction
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * Infiltrative adipose thissue within the muscle
| |
| * Absence of nuclear atypia
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * May be very small or more than 20 cm
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |[[File:Capture3.PNG|thumb|none|200px|Contributed by Dr. Dharam Ramnani in Webpathology]]
| |
| |-
| |
| ! style="padding: 5px 5px; background: #DCDCDC; " align="left" |Lipomas of Tendon Sheaths and Joints
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * Second and third decades of life
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * Female = male
| |
| * Lipoma of joints affects men more frequently than women
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * Most commonly seen in wrist and hand
| |
| * May also affect ankle and foot
| |
| * Bilateral and symmetric location in 50% of the cases
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * May cause severe pain, trigger finger, or even symptoms of carpal tunnel syndrome
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * May have 2 different shape:
| |
| * A single adipose tissue extending along the tendon sheet
| |
| * A lipomatous lesion composed mostly from hypertrophic synovial villi
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * Radiologic imaging may show a lesion of less density than the surrounding tissue
| |
| |style="padding: 5px 5px; background: #F5F5F5;" align="left" |_
| |
| |-
| |
| ! style="padding: 5px 5px; background: #DCDCDC; " align="left"|Lumbosacral Lipoma
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * First decade of life
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * Female > male
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * It occurs in the lumbosacral region and overlies the spine
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * Initially, asymptomatic
| |
| * Later signs and symptoms of progressive myelopathy or radiculopathy in the lower legs, bladder, or bowel
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * Uncapsulated mass that consists of lobulated adipose tissue
| |
| * Vascular proliferation and smooth muscle tissue may be present
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * Almost always associated with spina bifida or a similar laminar defect (lipomyeloschisis)
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |_
| |
| |-
| |
| ! style="padding: 5px 5px; background: #DCDCDC; " align="left"|Neural Fibrolipoma (Lipofibromatous Hamartoma of Nerves)
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * First three decades of life
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * Female > male (in the presence of macrodactyly)
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * Most commonly affect median nerve and its branches
| |
| * May also affect ulnar, radial, peroneal, and cranial nerves
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * May cause neuropathy, pain, paresthesia, and decreased sensation
| |
| * Carpal tunnel syndrome may also occur
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * A sausage-shaped mass with soft teture that has diffusely infiltrated a large nerve and its branches
| |
| * Fibrofatty tissue surronding and infiltrating the nerve trunk
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * Overgrowth of bone and macrodactyly of the digits innervated by the affected nerve is seen in one third of the cases
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |_
| |
| |}
| |
|
| |
|
| |
| ===Example #1===
| |
| The patient presented with S.O.B. one year after hysterectomy for a leiomyomatous uterus.
| |
| <div align="left">
| |
| <gallery heights="175" widths="175">
| |
| Image:Intravascular-extension-leiomyoma-001.jpg|CT in Intravenous leiomyomatosis
| |
| Image:Intravascular-extension-leiomyoma-002.jpg
| |
| </gallery>
| |
| </div>
| |
| <div align="left">
| |
| <gallery heights="175" widths="175">
| |
| Image:Intravascular-extension-leiomyoma-003.jpg
| |
| Image:Intravascular-extension-leiomyoma-004.jpg
| |
| </gallery>
| |
| </div>
| |
| <div align="left">
| |
| <gallery heights="175" widths="175">
| |
| Image:Intravascular-extension-leiomyoma-005.jpg
| |
| Image:Intravascular-extension-leiomyoma-006.jpg
| |
| </gallery>
| |
| </div>
| |
|
| |
| <div align="left">
| |
| <gallery heights="175" widths="175">
| |
| Image:Intravascular-extension-leiomyoma-007.jpg
| |
| Image:Intravascular-extension-leiomyoma-008.jpg
| |
| </gallery>
| |
| </div>
| |
| <references />
| |