Sandbox:Jaundice

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Differential diagnosis

Abbreviations: RUQ= Right upper quadrant of the abdomen, LUQ= Left upper quadrant, LLQ= Left lower quadrant, RLQ= Right lower quadrant, LFT= Liver function test, SIRS= Systemic inflammatory response syndrome, ERCP= Endoscopic retrograde cholangiopancreatography, IV= Intravenous, N= Normal, AMA= Anti mitochondrial antibodies, LDH= Lactate dehydrogenase, GI= Gastrointestinal, CXR= Chest X ray, IgA= Immunoglobulin A, IgG= Immunoglobulin G, IgM= Immunoglobulin M, CT= Computed tomography, PMN= Polymorphonuclear cells, ESR= Erythrocyte sedimentation rate, CRP= C-reactive protein

Classification of jaundice based on etiology Disease Clinical manifestations Diagnosis Comments
Symptoms Signs
Fever Rigors and chills Abdominal Pain Lab Findings Imaging
Hyperbilirubinema Unconjugated Hyperbilirubinemia Acute suppurative cholangitis
Acute cholangitis
Acute cholecystitis
Acute pancreatitis
Primary biliary cirrhosis
Primary sclerosing cholangitis
Cholelithiasis
Peptic ulcer disease
Gastritis
Gastroesophageal reflux disease
Gastric outlet obstruction
Gastrointestinal perforation
Acute appendicitis
Acute diverticulitis
Inflammatory bowel disease
Irritable bowel syndrome
Whipple's disease
Toxic megacolon
Tropical sprue
Celiac disease
Conjugated

Hyperbilirubinemia

Small intestine obstruction
Volvulus
Biliary colic
Renal colic
Mixed

Hyperbilirubinemia

Mesenteric ischemia
Acute ischemic colitis
Ruptured abdominal aortic aneurysm
Intra-abdominal or retroperitoneal hemorrhage
Non-hyperbilirubinemia causes of jaundice (false jaundice) Rifampin use
Beta caroten