Roseola history and symptoms: Difference between revisions

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{{Roseola}}
{{Roseola}}


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{{CMG}}; {{AE}}{{DAMI}}


==Overview==
==Overview==
The diagnosis of roseola is made clinically. However, in atypical cases, the diagnosis can be made by both serologic and direct detection of HHV6 virus in the saliva of the patient.<ref name="pmid25762531">{{cite journal| author=Agut H, Bonnafous P, Gautheret-Dejean A| title=Laboratory and clinical aspects of human herpesvirus 6 infections. | journal=Clin Microbiol Rev | year= 2015 | volume= 28 | issue= 2 | pages= 313-35 | pmid=25762531 | doi=10.1128/CMR.00122-14 | pmc=4402955 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25762531  }} </ref>
The hallmark of roseola is a non-pruritic [[macular]] or [[maculopapular]] rash. A positive history of a high [[fever]] of 40ºC (104ºF) that lasts for 3 to 5 days.<ref name="pmid25762531">{{cite journal| author=Agut H, Bonnafous P, Gautheret-Dejean A| title=Laboratory and clinical aspects of human herpesvirus 6 infections. | journal=Clin Microbiol Rev | year= 2015 | volume= 28 | issue= 2 | pages= 313-35 | pmid=25762531 | doi=10.1128/CMR.00122-14 | pmc=4402955 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25762531  }} </ref>


==History and symptoms==
==History and symptoms==
The hallmark of roseola is a non pruritic macular or maculopapular rash rash. A positive history of a high fever of 40ºC (104ºF) that lasts for 3 to 5 days.he
The hallmark of roseola is a non-pruritic [[macular]] or [[maculopapular]]  rash. A positive history of a high [[fever]] of 40ºC (104ºF) that lasts for 3 to 5 days.<ref name="pmid1315416">{{cite journal| author=Pruksananonda P, Hall CB, Insel RA, McIntyre K, Pellett PE, Long CE et al.| title=Primary human herpesvirus 6 infection in young children. | journal=N Engl J Med | year= 1992 | volume= 326 | issue= 22 | pages= 1445-50 | pmid=1315416 | doi=10.1056/NEJM199205283262201 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1315416  }} </ref><ref name="pmid8265302">{{cite journal| author=Asano Y, Yoshikawa T, Suga S, Kobayashi I, Nakashima T, Yazaki T et al.| title=Clinical features of infants with primary human herpesvirus 6 infection (exanthem subitum, roseola infantum). | journal=Pediatrics | year= 1994 | volume= 93 | issue= 1 | pages= 104-8 | pmid=8265302 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8265302  }} </ref>


===Common symptoms===
===Common symptoms===
*High fever 40ºC (104ºF)
*High [[fever]] 40ºC (104ºF)
*Rash
*[[Rash]]


===Less common symptoms===
===Less common symptoms===
*Irritability in infants and children
*Irritability in infants and children
*Mild diarrhea
*Mild [[diarrhea]]
*Decreased appetite
*[[Decreased appetite]]
*Swollen eyelids
*Swollen [[eyelids]]
*Injection of the tympanic membranes,
*Injection of the [[tympanic membrane]]
*Cervical or occipital lymphadenopathy  
*[[Cervical]] or [[occipital]] [[lymphadenopathy]]
*Red papules on the soft palate may be seen (Nagayama's spots)
*Red [[papules]] on the soft palate may be seen (Nagayama's spots)
*Uvulo-palatoglossal junction ulcers   
*Uvulo-palatoglossal junction [[ulcers]]  
*Bulging fontanelles,
*Bulging [[fontanelles]]
*Seizures,
*Encephalopathy
*Aseptic meningitis


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}
[[Category:Emergency mdicine]]
[[Category:Disease]]
[[Category:Up-To-Date]]
[[Category:Infectious disease]]
[[Category:Neurology]]
[[Category:Pediatrics]]
[[Category:Dermatology]]

Latest revision as of 00:03, 30 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Omodamola Aje B.Sc, M.D. [2]

Overview

The hallmark of roseola is a non-pruritic macular or maculopapular rash. A positive history of a high fever of 40ºC (104ºF) that lasts for 3 to 5 days.[1]

History and symptoms

The hallmark of roseola is a non-pruritic macular or maculopapular rash. A positive history of a high fever of 40ºC (104ºF) that lasts for 3 to 5 days.[2][3]

Common symptoms

Less common symptoms

References

  1. Agut H, Bonnafous P, Gautheret-Dejean A (2015). "Laboratory and clinical aspects of human herpesvirus 6 infections". Clin Microbiol Rev. 28 (2): 313–35. doi:10.1128/CMR.00122-14. PMC 4402955. PMID 25762531.
  2. Pruksananonda P, Hall CB, Insel RA, McIntyre K, Pellett PE, Long CE; et al. (1992). "Primary human herpesvirus 6 infection in young children". N Engl J Med. 326 (22): 1445–50. doi:10.1056/NEJM199205283262201. PMID 1315416.
  3. Asano Y, Yoshikawa T, Suga S, Kobayashi I, Nakashima T, Yazaki T; et al. (1994). "Clinical features of infants with primary human herpesvirus 6 infection (exanthem subitum, roseola infantum)". Pediatrics. 93 (1): 104–8. PMID 8265302.