Psoriasis overview

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Psoriasis is a disease which affects the skin and joints. It commonly causes red scaly patches to appear on the skin. The scaly patches caused by psoriasis, called psoriatic plaques, are areas of inflammation and excessive skin production. Skin rapidly accumulates at these sites and takes a silvery-white appearance. Plaques frequently occur on the skin of the elbows and knees, but can affect any area including the scalp and genitals. Psoriasis is hypothesized to be immune-mediated[1][2] and is not contagious.

The disorder is a chronic recurring condition which varies in severity from minor localized patches to complete body coverage. Fingernails and toenails are frequently affected (psoriatic nail dystrophy). Psoriasis can also cause inflammation of the joints, which is known as psoriatic arthritis. 10-15% of people with psoriasis have psoriatic arthritis.

References

  1. Hunziker T, Schmidli J. Psoriasis, an autoimmune disease? Ther Umsch. 1993 Feb;50(2):110-3. PMID 8456414
  2. Griffiths CE, Voorhees JJ. (1996). "Psoriasis, T cells and autoimmunity". J R Soc Med. 89 (6): 315–9. PMID 8758188.

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