Prolactinoma causes: Difference between revisions

Jump to navigation Jump to search
No edit summary
Line 1: Line 1:
__NOTOC__
__NOTOC__
{{Prolactinoma}}
{{Prolactinoma}}
{{CMG}} {{AE}}{{Faizan}}
{{CMG}} {{AE}}{{Anmol}}
==Overview==
==Overview==
There are no established causes for prolactinoma. Most [[pituitary]] tumors are sporadic.
There are no established causes for [[prolactinoma]]. Most cases of [[prolactinoma]] are [[sporadic]].


==Causes==
==Causes==
There are no established causes for prolactinoma. Most pituitary tumors are sporadic. A minority of prolactinomas are associated with [[familial]] syndromes.
There are no established causes for [[prolactinoma]]. Most cases of [[prolactinoma]] are [[sporadic]]. [[Prolactinoma]] may occur in approximately 30% of [[Multiple endocrine neoplasia type 1]].It may also occur with [[Carney complex]] or [[McCune-Albright syndrome]].<ref name="pmid16411062">{{cite journal| author=Ciccarelli A, Daly AF, Beckers A| title=The epidemiology of prolactinomas. | journal=Pituitary | year= 2005 | volume= 8 | issue= 1 | pages= 3-6 | pmid=16411062 | doi=10.1007/s11102-005-5079-0 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16411062  }} </ref>


===Familial Causes===
===Familial Causes<ref name="pmid16411062">{{cite journal| author=Ciccarelli A, Daly AF, Beckers A| title=The epidemiology of prolactinomas. | journal=Pituitary | year= 2005 | volume= 8 | issue= 1 | pages= 3-6 | pmid=16411062 | doi=10.1007/s11102-005-5079-0 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16411062  }} </ref><ref name="pmid17613551">{{cite journal| author=Karhu A, Aaltonen LA| title=Susceptibility to pituitary neoplasia related to MEN-1, CDKN1B and AIP mutations: an update. | journal=Hum Mol Genet | year= 2007 | volume= 16 Spec No 1 | issue=  | pages= R73-9 | pmid=17613551 | doi=10.1093/hmg/ddm036 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17613551  }} </ref>===


[[Prolactinoma]] may occur as part of a hereditary disorder called [[multiple endocrine neoplasia type 1]] ([[MEN 1]]). A minority of prolactinomas are associated with:<ref>http://radiopaedia.org/articles/pituitary-adenoma</ref>
[[Prolactinoma]] may occur as part of a [[hereditary disorder]] called [[multiple endocrine neoplasia type 1]] ([[MEN 1]]). A minority of [[prolactinoma]] are associated with:
*[[Multiple endocrine neoplasia type 1]] ([[MEN I]])
*[[Carney complex]]
*[[Carney complex]]
*[[McCune-Albright Syndrome]]
*[[McCune-Albright Syndrome]]
*MEN like syndrome (''CKDN1B'' loss of function)
*Isolated [[familial]] [[pituitary adenoma]]


=== Other Causes ===
=== Other Causes ===
Other causes include:
Other causes include:
*The xenoestrogenic chemical Bisphenol-A has been demonstrated to result in [[hyperprolactinaemia]] and growth of prolactin-producing pituitary cells.<ref>^ Goloubkova T, Ribeiro MF, Rodrigues LP, Cecconello AL, Spritzer PM (April 2000). "Effects of xenoestrogen bisphenol A on uterine and pituitary weight, serum prolactin levels and immunoreactive prolactin cells in ovariectomized Wistar rats". Arch. Toxicol. 74 (2): 92–8. doi:10.1007/s002040050658. PMID 10839476</ref> The increasing and prolonged exposure of Bisphenol-A from childhood may contribute to the development and growth of a [[prolactinoma]].
*The xenoestrogenic chemical Bisphenol-A has been demonstrated to result in [[hyperprolactinaemia]] and growth of [[Lactotroph|prolactin-producing pituitary cells]].<ref>^ Goloubkova T, Ribeiro MF, Rodrigues LP, Cecconello AL, Spritzer PM (April 2000). "Effects of xenoestrogen bisphenol A on uterine and pituitary weight, serum prolactin levels and immunoreactive prolactin cells in ovariectomized Wistar rats". Arch. Toxicol. 74 (2): 92–8. doi:10.1007/s002040050658. PMID 10839476</ref> The increasing and prolonged exposure of Bisphenol-A from childhood may contribute to the development and growth of a [[prolactinoma]].


== References ==
== References ==

Revision as of 20:03, 19 July 2017

Prolactinoma Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Prolactinoma from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

ECG

X-ray

Ultrasound

CT

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Prolactinoma causes On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Prolactinoma causes

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Prolactinoma causes

CDC on Prolactinoma causes

Prolactinoma causes in the news

Blogs on Prolactinoma causes

Directions to Hospitals Treating Prolactinoma

Risk calculators and risk factors for Prolactinoma causes

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Anmol Pitliya, M.B.B.S. M.D.[2]

Overview

There are no established causes for prolactinoma. Most cases of prolactinoma are sporadic.

Causes

There are no established causes for prolactinoma. Most cases of prolactinoma are sporadic. Prolactinoma may occur in approximately 30% of Multiple endocrine neoplasia type 1.It may also occur with Carney complex or McCune-Albright syndrome.[1]

Familial Causes[1][2]

Prolactinoma may occur as part of a hereditary disorder called multiple endocrine neoplasia type 1 (MEN 1). A minority of prolactinoma are associated with:

Other Causes

Other causes include:

References

  1. 1.0 1.1 Ciccarelli A, Daly AF, Beckers A (2005). "The epidemiology of prolactinomas". Pituitary. 8 (1): 3–6. doi:10.1007/s11102-005-5079-0. PMID 16411062.
  2. Karhu A, Aaltonen LA (2007). "Susceptibility to pituitary neoplasia related to MEN-1, CDKN1B and AIP mutations: an update". Hum Mol Genet. 16 Spec No 1: R73–9. doi:10.1093/hmg/ddm036. PMID 17613551.
  3. ^ Goloubkova T, Ribeiro MF, Rodrigues LP, Cecconello AL, Spritzer PM (April 2000). "Effects of xenoestrogen bisphenol A on uterine and pituitary weight, serum prolactin levels and immunoreactive prolactin cells in ovariectomized Wistar rats". Arch. Toxicol. 74 (2): 92–8. doi:10.1007/s002040050658. PMID 10839476

Template:WikiDoc Sources