Primary hyperaldosteronism causes: Difference between revisions

Jump to navigation Jump to search
No edit summary
 
(2 intermediate revisions by one other user not shown)
Line 3: Line 3:
{{CMG}}; {{AE}}{{HK}}
{{CMG}}; {{AE}}{{HK}}
==Overview==
==Overview==
Common causes of primary hyperaldosteronism include aldosterone-secreting adenoma, bilateral hyperplasia of the adrenal glands and ectopic secretion of aldosterone from ovaries and kidneys. Less common causes of primary hyperaldosteronism include familial hyperaldosteronism types I-III, pure aldosterone-producing adrenocortical carcinomas and unilateral hyperplasia of the adrenal gland.
Common causes of primary hyperaldosteronism are [[aldosterone]]-secreting [[adenoma]], bilateral [[hyperplasia]] of the [[Adrenal gland|adrenal glands]], and [[ectopic]] secretion of [[aldosterone]] from [[ovaries]] and [[kidneys]]. Less common causes of primary hyperaldosteronism are familial hyperaldosteronism types I-III, pure [[aldosterone]]-producing [[Adrenal carcinoma|adrenocortical carcinomas]], and unilateral [[hyperplasia]] of the [[adrenal gland]].


==Causes==
==Causes==
=== Common Causes ===
=== Common Causes ===
Common causes of Conn's Syndrome may be divided into:<ref name="urlPrimary aldosteronism: renaissance of a syndrome - Young - 2007 - Clinical Endocrinology - Wiley Online Library">{{cite web |url=http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2265.2007.02775.x/full |title=Primary aldosteronism: renaissance of a syndrome - Young - 2007 - Clinical Endocrinology - Wiley Online Library |author= |authorlink= |coauthors= |date= |format= |work= |publisher= |pages= |language= |archiveurl= |archivedate= |quote= |accessdate=}}</ref><ref name="pmid24944753">{{cite journal |vauthors=Aronova A, Iii TJ, Zarnegar R |title=Management of hypertension in primary aldosteronism |journal=World J Cardiol |volume=6 |issue=5 |pages=227–33 |year=2014 |pmid=24944753 |pmc=4062125 |doi=10.4330/wjc.v6.i5.227 |url= |issn=}}</ref>
Common causes of primary hyperaldosteronism (PA) may be divided into:<ref name="urlPrimary aldosteronism: renaissance of a syndrome - Young - 2007 - Clinical Endocrinology - Wiley Online Library">{{cite web |url=http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2265.2007.02775.x/full |title=Primary aldosteronism: renaissance of a syndrome - Young - 2007 - Clinical Endocrinology - Wiley Online Library |author= |authorlink= |coauthors= |date= |format= |work= |publisher= |pages= |language= |archiveurl= |archivedate= |quote= |accessdate=}}</ref><ref name="pmid24944753">{{cite journal |vauthors=Aronova A, Iii TJ, Zarnegar R |title=Management of hypertension in primary aldosteronism |journal=World J Cardiol |volume=6 |issue=5 |pages=227–33 |year=2014 |pmid=24944753 |pmc=4062125 |doi=10.4330/wjc.v6.i5.227 |url= |issn=}}</ref>
*Adrenal causes:
*[[Adrenal gland|Adrenal]] causes:
**Aldosterone-secreting adrenal adenoma (APA-benign tumor, 50-60%)
**[[Aldosterone]]-secreting [[Adrenal gland|adrenal]] [[adenoma]] (APA-[[benign tumor]], 50-60%)
**Idiopathic hyperaldosteronism (IHA-Bilateral hyperplasia of the adrenal gland, 40-50%)
**Idiopathic hyperaldosteronism (IHA-Bilateral [[hyperplasia]] of the [[adrenal gland]], 40-50%)
*Extra-adrenal causes
*Extra-adrenal causes
**Ectopic secretion of aldosterone (Ovaries and Kidneys)
**[[Ectopic]] secretion of [[aldosterone]] ([[ovaries]] and [[kidneys]])
===Less Common Causes===
===Less Common Causes===
Less common causes of primary hyperladosteronism include:<ref name="urlPrimary aldosteronism: renaissance of a syndrome - Young - 2007 - Clinical Endocrinology - Wiley Online Library2">{{cite web |url=http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2265.2007.02775.x/full |title=Primary aldosteronism: renaissance of a syndrome - Young - 2007 - Clinical Endocrinology - Wiley Online Library |author= |authorlink= |coauthors= |date= |format= |work= |publisher= |pages= |language= |archiveurl= |archivedate= |quote= |accessdate=}}</ref><ref name="pmid16003173">{{cite journal |vauthors=So A, Duffy DL, Gordon RD, Jeske YW, Lin-Su K, New MI, Stowasser M |title=Familial hyperaldosteronism type II is linked to the chromosome 7p22 region but also shows predicted heterogeneity |journal=J. Hypertens. |volume=23 |issue=8 |pages=1477–84 |year=2005 |pmid=16003173 |doi= |url= |issn=}}</ref>
Less common causes of primary hyperladosteronism include:<ref name="urlPrimary aldosteronism: renaissance of a syndrome - Young - 2007 - Clinical Endocrinology - Wiley Online Library2">{{cite web |url=http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2265.2007.02775.x/full |title=Primary aldosteronism: renaissance of a syndrome - Young - 2007 - Clinical Endocrinology - Wiley Online Library |author= |authorlink= |coauthors= |date= |format= |work= |publisher= |pages= |language= |archiveurl= |archivedate= |quote= |accessdate=}}</ref><ref name="pmid16003173">{{cite journal |vauthors=So A, Duffy DL, Gordon RD, Jeske YW, Lin-Su K, New MI, Stowasser M |title=Familial hyperaldosteronism type II is linked to the chromosome 7p22 region but also shows predicted heterogeneity |journal=J. Hypertens. |volume=23 |issue=8 |pages=1477–84 |year=2005 |pmid=16003173 |doi= |url= |issn=}}</ref><ref name="pmid22707896">{{cite journal |vauthors=Song MS, Seo SW, Bae SB, Kim YJ, Kim SJ |title=Aldosterone-producing adrenocortical carcinoma without hypertension |journal=Korean J. Intern. Med. |volume=27 |issue=2 |pages=221–3 |year=2012 |pmid=22707896 |pmc=3372808 |doi=10.3904/kjim.2012.27.2.221 |url= |issn=}}</ref>
*Familial hyperaldosteronism type I (glucocorticoid-remediable aldosteronism [GRA])
*Familial hyperaldosteronism type I ([[glucocorticoid]]-remediable aldosteronism [GRA])
*Familial hyperaldosteronism II (the familial occurrence of APA or bilateral idiopathic hyperplasia or both)
*Familial hyperaldosteronism type II (the familial occurrence of APA or bilateral idiopathic hyperplasia or both)
*Familial hyperaldosteronism type III (associated with the germline mutation in the KCNJ5 potassium channel)
*Familial hyperaldosteronism type III (associated with the [[germline mutation]] in the [[KCNJ5]] [[potassium channel]])
*Pure aldosterone-producing adrenocortical carcinomas
*Pure [[aldosterone]]-producing [[Adrenal carcinoma|adrenocortical carcinomas]]
*Unilateral adrenal hyperplasia
*Unilateral [[Adrenal gland|adrenal]] [[hyperplasia]]





Latest revision as of 16:48, 18 October 2017

Primary hyperaldosteronism Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Primary Hyperaldosteronism from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic study of choice

History and Symptoms

Physical Examination

Laboratory Findings

CT scan Findings

MRI Findings

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Case Studies

Case #1

Primary hyperaldosteronism causes On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Primary hyperaldosteronism causes

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Primary hyperaldosteronism causes

CDC on Primary hyperaldosteronism causes

Primary hyperaldosteronism causes in the news

Blogs on Primary hyperaldosteronism causes

Directions to Hospitals Treating Conn syndrome

Risk calculators and risk factors for Primary hyperaldosteronism causes

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Syed Hassan A. Kazmi BSc, MD [2]

Overview

Common causes of primary hyperaldosteronism are aldosterone-secreting adenoma, bilateral hyperplasia of the adrenal glands, and ectopic secretion of aldosterone from ovaries and kidneys. Less common causes of primary hyperaldosteronism are familial hyperaldosteronism types I-III, pure aldosterone-producing adrenocortical carcinomas, and unilateral hyperplasia of the adrenal gland.

Causes

Common Causes

Common causes of primary hyperaldosteronism (PA) may be divided into:[1][2]

Less Common Causes

Less common causes of primary hyperladosteronism include:[3][4][5]


References

  1. "Primary aldosteronism: renaissance of a syndrome - Young - 2007 - Clinical Endocrinology - Wiley Online Library".
  2. Aronova A, Iii TJ, Zarnegar R (2014). "Management of hypertension in primary aldosteronism". World J Cardiol. 6 (5): 227–33. doi:10.4330/wjc.v6.i5.227. PMC 4062125. PMID 24944753.
  3. "Primary aldosteronism: renaissance of a syndrome - Young - 2007 - Clinical Endocrinology - Wiley Online Library".
  4. So A, Duffy DL, Gordon RD, Jeske YW, Lin-Su K, New MI, Stowasser M (2005). "Familial hyperaldosteronism type II is linked to the chromosome 7p22 region but also shows predicted heterogeneity". J. Hypertens. 23 (8): 1477–84. PMID 16003173.
  5. Song MS, Seo SW, Bae SB, Kim YJ, Kim SJ (2012). "Aldosterone-producing adrenocortical carcinoma without hypertension". Korean J. Intern. Med. 27 (2): 221–3. doi:10.3904/kjim.2012.27.2.221. PMC 3372808. PMID 22707896.

Template:WH Template:WS