Primary ciliary dyskinesia history and symptoms: Difference between revisions

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{{Primary ciliary dyskinesia}}
{{Primary ciliary dyskinesia}}


{{CMG}}
{{CMG}} {{AE}}{{Hafsa}}
==Overview==
Patients with [[Primary ciliary dyskinesia CT|primary ciliary dyskinesia]] may present in early [[infancy]] with [[respiratory distress]] or later in life with [[chronic bronchitis]], persistent [[rhinorrhea]], [[sinusitis]], [[bronchiectasis]], or male [[infertility]].


==Overview==
==History and Symptoms==
==History and Symptoms==
The main consequence of impaired ciliary function is reduced or absent [[mucus]] clearance in the [[lung]]s, and susceptibility to chronic, recurrent respiratory infections, including [[sinusitis]], [[bronchitis]], [[pneumonia]], and [[otitis media]]. Susceptibility to these infections can be drastically reduced by an early diagnosis, as treatment with various chest physiotherapy techniques during childhood helps prevent the lungs being damaged or colonised by infection during this vulnerable period. Many patients experience [[hearing loss]] and show symptoms of [[otitis media|glue ear]] which demonstrate variable responsiveness to the insertion of myringotomy tubes or [[grommet|grommets]]. A poor sense of smell accompanies high [[mucus]] production in the sinuses.  [[Infertility]] is common, but IVF techniques have been successful for some parents with PCD. Clinical progression of the disease is variable with lung [[organ transplant|transplantation]] required in severe cases. For most patients, aggressive measures to enhance clearance of mucus, prevent respiratory infections, and treat bacterial super infections are recommended.
 
*The patients with primary ciliary dyskinesia may have a history of,
 
*Persistent [[rhinorrhea]], the sensation of local fullness, and painful [[sinus]].
*[[Anosmia]] and [[halitosis]].
*Recurrent [[otitis media]].
*Recurrent [[sinusitis]].
*[[Hydrocephalus]] in a few cases.
*[[Male infertility]] is most common.
*Chronic [[productive cough]].
*[[Bronchospasm|Bronchospastic]] symptoms (eg, [[wheeze]] and [[cough]]), usually responsive to [[bronchodilator]] therapy.
*Recurrent or persistent [[atelectasis]] or [[pneumonia]].<ref>{{cite web |url=https://emedicine.medscape.com/article/1002319-clinical#b1 |title=Primary Ciliary Dyskinesia Clinical Presentation: History, Physical, Causes |format= |work= |accessdate=}}</ref>
 
==References==
==References==
{{Reflist|2}}
{{Reflist|2}}
{{WH}}
{{WS}}


[[Category:Genetic disorders]]
[[Category:Genetic disorders]]
[[Category:Pulmonology]]
[[Category:Pulmonology]]
[[Category:Cardiology]]
[[Category:Cardiology]]
{{WH}}
{{WS}}

Latest revision as of 13:50, 4 September 2021

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Hafsa Ghaffar, M.B.B.S[2]

Overview

Patients with primary ciliary dyskinesia may present in early infancy with respiratory distress or later in life with chronic bronchitis, persistent rhinorrhea, sinusitis, bronchiectasis, or male infertility.

History and Symptoms

  • The patients with primary ciliary dyskinesia may have a history of,

References

  1. "Primary Ciliary Dyskinesia Clinical Presentation: History, Physical, Causes".

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