Polycythemia history and symptoms: Difference between revisions

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===Symptoms===
===Symptoms===
Common symptoms of PV include:<ref name="pmid29437189">{{cite journal| author=Lelonek E, Matusiak Ł, Wróbel T, Szepietowski JC| title=Aquagenic Pruritus in Polycythemia Vera: Clinical Characteristics. | journal=Acta Derm Venereol | year= 2018 | volume= 98 | issue= 5 | pages= 496-500 | pmid=29437189 | doi=10.2340/00015555-2906 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29437189  }}</ref><ref name="pmid20597963">{{cite journal| author=Saini KS, Patnaik MM, Tefferi A| title=Polycythemia vera-associated pruritus and its management. | journal=Eur J Clin Invest | year= 2010 | volume= 40 | issue= 9 | pages= 828-34 | pmid=20597963 | doi=10.1111/j.1365-2362.2010.02334.x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20597963  }}</ref><ref name="pmid1587207">{{cite journal| author=Murphy S| title=Polycythemia vera. | journal=Dis Mon | year= 1992 | volume= 38 | issue= 3 | pages= 153-212 | pmid=1587207 | doi=10.1016/0011-5029(92)90002-7 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1587207  }}</ref><ref name="pmid9387203">{{cite journal| author=Michiels JJ| title=Erythromelalgia and vascular complications in polycythemia vera. | journal=Semin Thromb Hemost | year= 1997 | volume= 23 | issue= 5 | pages= 441-54 | pmid=9387203 | doi=10.1055/s-2007-996121 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9387203  }}</ref>
Common symptoms of PV include:<ref name="pmid29437189">{{cite journal| author=Lelonek E, Matusiak Ł, Wróbel T, Szepietowski JC| title=Aquagenic Pruritus in Polycythemia Vera: Clinical Characteristics. | journal=Acta Derm Venereol | year= 2018 | volume= 98 | issue= 5 | pages= 496-500 | pmid=29437189 | doi=10.2340/00015555-2906 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29437189  }}</ref><ref name="pmid20597963">{{cite journal| author=Saini KS, Patnaik MM, Tefferi A| title=Polycythemia vera-associated pruritus and its management. | journal=Eur J Clin Invest | year= 2010 | volume= 40 | issue= 9 | pages= 828-34 | pmid=20597963 | doi=10.1111/j.1365-2362.2010.02334.x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20597963  }}</ref><ref name="pmid1587207">{{cite journal| author=Murphy S| title=Polycythemia vera. | journal=Dis Mon | year= 1992 | volume= 38 | issue= 3 | pages= 153-212 | pmid=1587207 | doi=10.1016/0011-5029(92)90002-7 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1587207  }}</ref><ref name="pmid9387203">{{cite journal| author=Michiels JJ| title=Erythromelalgia and vascular complications in polycythemia vera. | journal=Semin Thromb Hemost | year= 1997 | volume= 23 | issue= 5 | pages= 441-54 | pmid=9387203 | doi=10.1055/s-2007-996121 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9387203 }}</ref><ref name="pmid23855810">{{cite journal| author=Sekhar M, McVinnie K, Burroughs AK| title=Splanchnic vein thrombosis in myeloproliferative neoplasms. | journal=Br J Haematol | year= 2013 | volume= 162 | issue= 6 | pages= 730-47 | pmid=23855810 | doi=10.1111/bjh.12461 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23855810 }}</ref>


*[[Dizziness]] or [[vertigo]]
*[[Dizziness]] or [[vertigo]]

Latest revision as of 15:07, 4 March 2021

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Debduti Mukhopadhyay, M.B.B.S[2] Zaida Obeidat, M.D.

Overview

The hallmark symptoms of polycythemia vera are headaches, dizziness, erythromelalgia, abdominal fullness due to splenomegaly, etc.

History and Symptoms

  • Clinical course is insidious, more commonly it is noticed as an incidental finding on a routine blood test. Patients may present with nonspecific findings like fatigue, headache, dizziness, itchiness, especially after a warm shower. Bloating or "fullness" is also sometimes reported due to marked splenomegaly.
  • If adequately managed, the natural course of the disease tends to be long. The cause of death remains unknown in a large majority of cases. Other causes of death include acute leukemia, malignancies secondary to the disease, thrombotic complications, cardiac failure, and natural progression of the disease. [1]

Symptoms

Common symptoms of PV include:[2][3][4][5][6]

References

  1. Büyükaşik Y, Alİ R, Ar C, Turgut M, Yavuz S, Saydam G (August 2018). "Polycythemia vera: diagnosis, clinical course, and current management". Turk J Med Sci. 48 (4): 698–710. doi:10.3906/sag-1806-43. PMID 30114348.
  2. Lelonek E, Matusiak Ł, Wróbel T, Szepietowski JC (2018). "Aquagenic Pruritus in Polycythemia Vera: Clinical Characteristics". Acta Derm Venereol. 98 (5): 496–500. doi:10.2340/00015555-2906. PMID 29437189.
  3. Saini KS, Patnaik MM, Tefferi A (2010). "Polycythemia vera-associated pruritus and its management". Eur J Clin Invest. 40 (9): 828–34. doi:10.1111/j.1365-2362.2010.02334.x. PMID 20597963.
  4. Murphy S (1992). "Polycythemia vera". Dis Mon. 38 (3): 153–212. doi:10.1016/0011-5029(92)90002-7. PMID 1587207.
  5. Michiels JJ (1997). "Erythromelalgia and vascular complications in polycythemia vera". Semin Thromb Hemost. 23 (5): 441–54. doi:10.1055/s-2007-996121. PMID 9387203.
  6. Sekhar M, McVinnie K, Burroughs AK (2013). "Splanchnic vein thrombosis in myeloproliferative neoplasms". Br J Haematol. 162 (6): 730–47. doi:10.1111/bjh.12461. PMID 23855810.

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