Polycythemia epidemiology and demographics: Difference between revisions
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===Case-fatality rate/Mortality rate=== | ===Case-fatality rate/Mortality rate=== | ||
* | * 4 year mortality rate is >10%. | ||
* | *On an average patients lived with the disease for 8.6 years (mean), the cases that were fatal were approximately 77.1 years of age on average. | ||
*Comorbidities such as cardiovascular diseases, other blood and lymphatic disorders, vascular disorders, mass occupying lesions in the thorax, respiratory system, infections, etc accounted for more deaths more often. | |||
*Thrombotic complications were the most common cause of death followed by hematologic malignancy. <ref name="urlwww.hematologyadvisor.com">{{cite web |url=https://www.hematologyadvisor.com/home/conference-coverage/ash-2020/assessing-mortality-rates-causes-of-death-in-polycythemia-vera/ |title=www.hematologyadvisor.com |format= |work= |accessdate=}}</ref> | |||
===Age=== | ===Age=== |
Revision as of 02:52, 9 December 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Debduti Mukhopadhyay, M.B.B.S[2]
Overview
Epidemiology and Demographics
Incidence
- The incidence of polycythemia vera is approximately 1.9 per 100,000 individuals in the United States.
- Taking into account all races and ethnicities, the incidence is approximately 2.8 per 100,000 males and 1.3 per 100,000 in females. [1]
Prevalence
- The prevalence of polycythemia vera in the 7 MM countries was 283,442 in 2017.
- Prevalence of polycythemia vera was the highest in the US in 2017 at 157,290, out of which 62,916 cases were asymptomatic and 94,374 were symptomatic. [2]
- 22 cases per 100,000 people. [1]
Case-fatality rate/Mortality rate
- 4 year mortality rate is >10%.
- On an average patients lived with the disease for 8.6 years (mean), the cases that were fatal were approximately 77.1 years of age on average.
- Comorbidities such as cardiovascular diseases, other blood and lymphatic disorders, vascular disorders, mass occupying lesions in the thorax, respiratory system, infections, etc accounted for more deaths more often.
- Thrombotic complications were the most common cause of death followed by hematologic malignancy. [3]
Age
- It has been noted that PV is more common in the age group >75. [2]
- Median age of diagnosis is 60. [4]
- The incidence of [disease name] increases with age; the median age at diagnosis is [#] years.
- [Disease name] commonly affects individuals younger than/older than [number of years] years of age.
- [Chronic disease name] is usually first diagnosed among [age group].
- [Acute disease name] commonly affects [age group].
Race
- Jews of Eastern European descent have a higher number of cases as compared to other Europeans or Asians. [1]
Gender
- Generally, there is no sex predeliction.[4]
- In the analysis for the 7 MM countries, the percentage of prevalent males was higher than prevalent females. [2]
Region
- The majority of [disease name] cases are reported in [geographical region].
- [Disease name] is a common/rare disease that tends to affect [patient population 1] and [patient population 2].