Polyarteritis nodosa epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Ali Poyan Mehr, M.D. [2] Associate Editor(s)-in-Chief: Olufunmilola Olubukola M.D.[3]

Overview

Epidemiology and Demographics

Prevalence

Incidence

Age

Gender

Race

PAN is a very uncommon disease and a rare form of vasculitis. Population prevalence estimates for polyarteritis nodosa (PAN) range from 2 to 33 per million across the European Countries [1] and the annual incidence in three regions of Europe was estimated to be 4.4 to 9.7 per million [2].

PAN is commoner in men than women at a predominance rate of 1.5: 1 [3]. It occurs in all ethnic groups. Most cases of PAN occur in the 5th to 6th decade of life. It can also occur in children although this form of presentation is very rare. PAN has been associated with hepatitis B virus infection.

References

  1. Mohammad AJ, Jacobsson LT, Mahr AD, Sturfelt G, Segelmark M (2007). "Prevalence of Wegener's granulomatosis, microscopic polyangiitis, polyarteritis nodosa and Churg-Strauss syndrome within a defined population in southern Sweden". Rheumatology (Oxford). 46 (8): 1329–37. doi:10.1093/rheumatology/kem107. PMID 17553910.
  2. Watts RA, Lane SE, Bentham G, Scott DG (2000). "Epidemiology of systemic vasculitis: a ten-year study in the United Kingdom". Arthritis Rheum. 43 (2): 414–9. doi:10.1002/1529-0131(200002)43:2<414::AID-ANR23>3.0.CO;2-0. PMID 10693883.
  3. Mahr A, Guillevin L, Poissonnet M, Aymé S (2004). "Prevalences of polyarteritis nodosa, microscopic polyangiitis, Wegener's granulomatosis, and Churg-Strauss syndrome in a French urban multiethnic population in 2000: a capture-recapture estimate". Arthritis Rheum. 51 (1): 92–9. doi:10.1002/art.20077. PMID 14872461.

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