Polyarteritis nodosa diagnostic criteria
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]; Haritha Machavarapu, M.B.B.S.
Overview
Diagnostic Criteria
A patient is said to have polyarteritis nodosa if he or she has 3 of the 10 following signs:
- Weight loss ≥4 kg.
- Livedo reticularis (a mottled purplish skin discoloration over the extremities or torso).
- Testicular pain or tenderness. (occasionally, a site biopsied for diagnosis).
- Muscle pain, weakness, or leg tenderness.
- Nerve disease (either single or multiple).
- Diastolic blood pressure greater than 90mmHg (high blood pressure).
- Elevated kidney blood tests (BUN greater than 40 mg/dl or creatinine greater than 1.5 mg/dl).
- Hepatitis B virus tests positive (for surface antigen or antibody).
- Arteriogram (angiogram) showing the arteries that are dilated (aneurysms) or constricted by the blood vessel inflammation.
- Biopsy of tissue showing the arteritis (typically inflamed arteries).