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{{Pneumomediastinum}}
{{Pneumomediastinum}}
{{CMG}}; {{AE}}  
{{CMG}}; {{AE}} {{Trusha}}
 
==Overview==
The condition was first described in 1819 by [[René Laennec]]. In 1939, Louis Hamman described primary or spontaneous pneumomediastinum which is why it is also known as [[Hamman's syndrome]]. Macklin and Macklin, in 1944 provided a sound explanation for pneumomediastinum, based on experiments conducted on cats: the increase of [[Intra alveolar pressure|alveolar pressure]] causes them to rupture, therefore releasing air which in turn migrates through the [[Peribronchial cuffing|peribronchial]] and perivascular sheaths to the [[mediastinum]].


==Historical Perspective==
==Historical Perspective==
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===Discovery===
===Discovery===
*The condition was first described in 1819 by [[René Laennec]]. <ref>Laënnec RTH. De l’auscultation médiate ou Traité du Diagnostic des Maladies des Poumon et du Coeur. 1st ed. Paris: Brosson & Chaudé; 1819.</ref><ref name="pmid17048358">{{cite journal |author=Roguin A |title=Rene Theophile Hyacinthe Laënnec (1781-1826): the man behind the stethoscope |journal=Clinical medicine & research |volume=4 |issue=3 |pages=230–5 |year=2006 |pmid=17048358 |doi=}}</ref>
*The condition was first described in 1819 by [[René Laennec]]. <ref>Laënnec RTH. De l’auscultation médiate ou Traité du Diagnostic des Maladies des Poumon et du Coeur. 1st ed. Paris: Brosson & Chaudé; 1819.</ref><ref name="pmid17048358">{{cite journal |author=Roguin A |title=Rene Theophile Hyacinthe Laënnec (1781-1826): the man behind the stethoscope |journal=Clinical medicine & research |volume=4 |issue=3 |pages=230–5 |year=2006 |pmid=17048358 |doi=}}</ref>
*[Disease name] was first discovered by [name of scientist], a [nationality + occupation], in [year]/during/following [event].
*Later in 1939, Louis Hamman described primary or spontaneous pneumomediastinum which is why it is also known as [[Hamman's syndrome]]. He described a [[Post-partum|post-partum patient]] with [[subcutaneous emphysema]] and pneumomediastinum, a case known in current times as [[Hamman’s syndrome]].<ref>Hamman L. Spontaneous mediastinal emphysema. Bull Johns Hopkins Hosp 1939;64:1-21</ref>
 
*Macklin and Macklin, in 1944 provided a sound explanation for pneumomediastinum, based on experiments conducted on cats: the increase of [[Intra alveolar pressure|alveolar pressure]] causes them to rupture, therefore releasing air which in turn migrates through the [[Peribronchial cuffing|peribronchial]] and perivascular sheaths to the [[mediastinum]].<ref>MACKLIN MADGE THURLOW; MACKLIN, CHARLES C. Medicine: December 1944 - Volume 23 - Issue 4 - ppg 281-358</ref>
*The association between [important risk factor/cause] and [disease name] was made in/during [year/event].
*In [year], [scientist] was the first to discover the association between [risk factor] and the development of [disease name].
*In [year], [gene] mutations were first implicated in the pathogenesis of [disease name].
 
==Outbreaks==
There have been several outbreaks of [disease name], which are summarized below:
 
==Landmark Events in the Development of Treatment Strategies==
In [year], [diagnostic test/therapy] was developed by [scientist] to treat/diagnose [disease name].
 
==Impact on Cultural History==
 
==Famous Cases==
The following are a few famous cases of [[disease name]]:


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}
[[Category:Pulmonology]]
[[Category:Medicine]]
[[Category:Surgery]]
[[Category:Cardiology]]
[[Category:Emergency medicine]]


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[[Category: (name of the system)]]

Latest revision as of 13:52, 18 December 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Trusha Tank, M.D.[2]

Overview

The condition was first described in 1819 by René Laennec. In 1939, Louis Hamman described primary or spontaneous pneumomediastinum which is why it is also known as Hamman's syndrome. Macklin and Macklin, in 1944 provided a sound explanation for pneumomediastinum, based on experiments conducted on cats: the increase of alveolar pressure causes them to rupture, therefore releasing air which in turn migrates through the peribronchial and perivascular sheaths to the mediastinum.

Historical Perspective

Discovery

References

  1. Laënnec RTH. De l’auscultation médiate ou Traité du Diagnostic des Maladies des Poumon et du Coeur. 1st ed. Paris: Brosson & Chaudé; 1819.
  2. Roguin A (2006). "Rene Theophile Hyacinthe Laënnec (1781-1826): the man behind the stethoscope". Clinical medicine & research. 4 (3): 230–5. PMID 17048358.
  3. Hamman L. Spontaneous mediastinal emphysema. Bull Johns Hopkins Hosp 1939;64:1-21
  4. MACKLIN MADGE THURLOW; MACKLIN, CHARLES C. Medicine: December 1944 - Volume 23 - Issue 4 - ppg 281-358

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